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Carbetocin Acetate

Carbetocin Acetate

Product ID C0175
Cas No. 37025-55-1
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $454.20 In stock
25 mg $1,297.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Carbetocin is an analog of oxytocin that exhibits mood-modulatory characteristics such as anxiolytic and antidepressant activities. Carbetocin is clinically used to prevent postpartum hemorrhaging. In animal models of opioid dependency, carbetocin attenuates the negative aspects of withdrawal and prevents stress-induced reinstatement in a conditioned place preference (CPP) paradigm, indicating potential benefit as a relapse prevention therapy. Additionally, carbetocin decreases immobility time in animals undergoing the forced swim test and increases motor activity and time spent in open areas in the elevated plus maze and open field test. Carbetocin likely binds OXTR receptors.

Product Info

Cas No.

37025-55-1

Purity

≥95%

Formula

C45H69N11O12S

Formula Wt.

988.17

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0175 MSDS PDF

Info Sheet

C0175 Info Sheet PDF

References

Zanos P, Georgiou P, Wright SR, et al. The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice. Neuropsychopharmacology. 2014 Mar;39(4):855-65. PMID: 24129263.

Samimi M, Imani-Harsini A, Abedzadeh-Kalahroudi M. Carbetocin vs. Syntometrine in Prevention of Postpartum Hemorrhage: a Double Blind Randomized Control Trial. Iran Red Crescent Med J. 2013 Sep;15(9):817-22. PMID: 24616793.

Klenerova V, Krejci I, Sida P, et al. Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats. Neuro Endocrinol Lett. 2010;31(5):622-30. PMID: 21173744.

Chaviaras S, Mak P, Ralph D, et al. Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test. Psychopharmacology (Berl). 2010 May;210(1):35-43. PMID: 20232054.

Custom Order

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