• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Catharanthine base

Catharanthine base

Product ID C0376
Cas No. 2468-21-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $54.60 In stock
25 mg $102.30 In stock
100 mg $170.40 In stock
500 mg $306.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Catharanthine is an alkaloid found in Catharanthus that is a chemical precursor in the synthesis of vinca alkaloids such as vinblastine and vincristine. Catharanthine displays weak anti-mitotic activity, binding tubulin poorly. Catharanthine exhibits anti-parasitic, vasodilatory, and antihypertensive activities. This compound shows antimalarial benefit against species of Plasmodium. In vivo, catharanthine inhibits voltage-gated Ca2+ channel currents, decreasing blood pressure and heart rate.

Product Info

Cas No.

2468-21-5

Purity

≥98%

Formula

C21H24N2O2

Formula Wt.

336.43

IUPAC Name

methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate

Melting Point

138-140°C

Appearance

Almost White Crystalline Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C0376 MSDS PDF

Info Sheet

C0376 Info Sheet PDF

References

Munigunti R, Becker K, Brun R, et al. Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR. Nat Prod Commun. 2013 Aug;8(8):1135-6. PMID: 24079187.

Jadhav A, Liang W, Papageorgiou PC, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92. PMID: 23532933.

Sertel S, Fu Y, Zu Y, et al. Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine. Biochem Pharmacol. 2011 Mar 15;81(6):723-35. PMID: 21219884.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P600006

    RP-6306

    PKMYT1 inhibitor

    ≥98%
  • B1855

    O6-Benzylguanine

    MGMT inhibitor.

    ≥98%
  • C5782

    Coumarin

    Benzopyrone found in various plants, precursor ...

    ≥98%
  • G124084

    GDC-0973

    MEK1 inhibitor.

    ≥99%
  • A4497

    Alyssin Sulfone

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • F4782

    Fludarabine Phosphate

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • P3456

    Pimobendan

    PDE3 inhibitor.

    ≥99%
  • C4559

    Clomiphene Citrate

    Used for in vitro fertilization; FIASMA, SERM.<...

    ≥98%
  • T1952

    Tenuazonic Acid Copper Salt

    Mycotoxin produced by Alternaria; photosynthesi...

    ≥98%
  • A6934

    Aristolochic Acid C

    Found in Aristolochia and Radix; potential PLA2...

    ≥94%
  • R0348

    Ramelteon

    Melatonin analog; MT1/2 agonist.

    ≥99%
  • C1876

    Cetirizine Dihydrochloride

    Histamine H1 antagonist.

    ≥99%
  • B1992

    Bexarotene

    RXR agonist.

    ≥98%
  • C104761

    CCT-196969

    pan-Raf inhibitor.

    ≥98%
  • C294458

    Chlorzoxazone

    Centrally acting muscle relaxant.

    ≥99%
  • T1656

    Tenoxicam Impurity B

    Tenoxicam impurity

    ≥98%
  • P5845

    Polydatin

    Stilbenoid glucoside found in Polygonum.

    ≥97%
  • T1778

    2,3,5,6-Tetramethylpyrazine

    Dihydropyrazine found in Ligusticum walliichi. ...

    ≥98%
  • C1620

    Ceftiofur Hydrochloride

    β-lactam; penicillin binding protein inhibitor...

    ≥90%
  • P2515

    3-Phenylpropyl Isothiocyanate

    Synthetic ITC.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only