Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1354545-57-5 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 • CH4O3S |
Formula Wt. | 635.18 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate (1:1) |
Synonym | CEP 28122 Mesylate, CEP28122 Mesylate |
Solubility | 10 mM in DMSO |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Docetaxel impurity
Perfluorinated insecticide.
Triterpene saponin found in Bupleurum.
Jumonji histone demethylase inhibitor.
Synthetic type II pyrethroid insecticide; prote...
Protein synthesis inhibitor, DPP2 and metallope...
Vitamin E component
GPR84 agonist.
Optically active cysteine derivative found in A...
Steroidal jerveratrum alkaloid found in Veratru...
α1-adrenergic antagonist.
Endogenous peptide; FPRL1/2 agonist.
p53 activator.
Prodrug
Histamine H2 antagonist, GSK-3β inhibitor.
β-lactam cephalosporin; penicillin binding pro...
p38 MAPK inhibitor.
Azapirone; α1-adrenergic and 5-HT1A partial ag...
Anti-tuberculosis
p110α inhibitor.