Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Product Unit Size | Cost | Quantity | Stock |
---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
Cas No. | 1354545-57-5 |
---|---|
Purity | ≥98% |
Formula | C28H35ClN6O3 • CH4O3S |
Formula Wt. | 635.18 |
IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate (1:1) |
Synonym | CEP 28122 Mesylate, CEP28122 Mesylate |
Solubility | 10 mM in DMSO |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Imidazole; 14-α demethylase inhibitor.
Antioxidant; Nrf2 activator.
Polymixin, antimicrobial peptide, induces forma...
Mycotoxin produced by Aspergillus; actin polyme...
Inhibitor of ALK2, ALK3, ALK6, and AMPK.
Modified nucleotide used for labeling DNA; DNA ...
Glycopeptide, binds D-Ala-D-Ala; cell wall synt...
Diterpene found in Taxus; potential microtubule...
Chalcone; SIRT activator, GABA-A positive modul...
Neuropeptide found in Schistocera gregaria.
Endogenous neuropeptide hormone; somatostatin a...
Found in Aristolochia and Radix; potential PLA2...
Triterpene glycoside found in Glycyrrhiza; 15-H...
5-Fluorouracil derivative, fluorinated pyrimidi...
Alkaloid found in species of Loranthus, Calia, ...
Polyether neurotoxin found in Karenia brevis; N...
Statin; HMG-CoA reductase inhibitor, potential ...
Indole derivative found in Isatis, Calanthe, an...
Found in Aconitum bulleyanum; voltage-gated Na+...
Synthetic peptide; dermorphin analog; δOR and ...