Description
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
CEP-28122 is an ALK inhibitor. It inhibits tumor growth in ALK positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroglastoma cells.
| Cas No. | 1354545-57-5 |
|---|---|
| Purity | ≥98% |
| Formula | C28H35ClN6O3 • CH4O3S |
| Formula Wt. | 635.18 |
| IUPAC Name | (1S,2S,3R,4R)-3-[(5-Chloro-2-{[(7S)-1-methoxy-7-(4-morpholinyl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}-4-pyrimidinyl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonate (1:1) |
| Synonym | CEP 28122 Mesylate, CEP28122 Mesylate |
| Solubility | 10 mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Cheng M., Quail M., et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 11(3):670-79 (2012). PMID: 22203728.
Antimicrobial peptide found in bee and wasp ven...
Fluoroquinolone; topoisomerase IV and bacterial...
Macrolide; vacuolar H+-ATPase inhibitor.
Naturally produced ITC, sulfonyl analog of sulf...
Pesticide; demethylation inhibitor.
HDM2 inhibitor
Analog of staurosporine.
FGFR inhibitor.
Quinoline, food preservative; HSP90 inhibitor.<...
Cytarabine derivative, nucleoside (cytosine) an...
PLK4 inhibitor.
Dihydropyridine; L-type Ca2+ channel blocker.
Polyphenol found in olive oil, antioxidant.
Diamidine; ACE2 activator, DNA polymerase inhib...
Antimicrobial peptide found in frogs, induces p...
Diterpene found in coffee beans.
Endogenous neuropeptide, also known as substanc...
Jumonji histone demethylase inhibitor.
Endogenous steroid hormone, estriol precursor; ...
Selective inhibitor of LRRK2.