• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Cladribine

Cladribine

Product ID C4402
Cas No. 4291-63-8
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $92.00 In stock
10 mg $153.10 In stock
25 mg $306.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cladribine is a deoxyadenosine analog that exhibits immunosuppressive and anticancer chemotherapeutic activities. Cladribine is used clinically to treat hairy cell leukemia and has shown mixed results as a potential treatment for multiple sclerosis. Cladribine induces apoptosis in monocyte-derived dendritic cells. Across many cellular models, this compound decreases levels of circulating B and T lymphocytes and inhibits growth of both proliferating and quiescent cells. As a nucleoside analog, cladribine inhibits DNA polymerase and ribonucleotide reductase, suppressing DNA repair and synthesis.

Product Info

Cas No.

4291-63-8

Purity

≥98%

Formula

C10H12ClN5O3

Formula Wt.

285.69

IUPAC Name

(2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Synonym

2-CdA, 2-Chlorodeoxyadenosine

Melting Point

210-220C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C4402 MSDS PDF

Info Sheet

C4402 Info Sheet PDF

References

Singh V, Prajeeth CK, Gudi V, et al. 2-Chlorodeoxyadenosine (cladribine) induces apoptosis in human monocyte-derived dendritic cells. Clin Exp Immunol. 2013 Aug;173(2):288-97. PMID: 23607690.

Comi G, Hartung HP, Kurukulasuriya NC, et al. Cladribine tablets for the treatment of relapsing-remitting multiple sclerosis. Expert Opin Pharmacother. 2013 Jan;14(1):123-36. PMID: 23256518.

Leist TP, Weissert R. Cladribine: mode of action and implications for treatment of multiple sclerosis. Clin Neuropharmacol. 2011 Jan-Feb;34(1):28-35. PMID: 21242742.

Robak T, Korycka A, Robak E. Older and new formulations of cladribine. Pharmacology and clinical efficacy in hematological malignancies. Recent Pat Anticancer Drug Discov. 2006 Jan;1(1):23-38. PMID: 18221024.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T176503

    Temsirolimus

    Analog of rapamycin.

    ≥98%
  • P3568

    Pirarubicin

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • A4847

    Amylin, human

    Endogenous peptide hormone inolved in gastric e...

    ≥95%
  • S8098

    SU-1498

    Tyrphostin; VEGFR inhibitor.

    ≥99%
  • P200002

    PF-07321332

    Inhibitor of coronaviruses

    ≥99%
  • A7668

    Atracurium Besylate

    Non-depolarizing NMJ blocker; AChR antagonist.<...

    ≥95%
  • P600006

    RP-6306

    PKMYT1 inhibitor

    ≥98%
  • A7203

    AS-703026

    MEK1/2 inhibitor.

    ≥98%
  • B4402

    Blasticidin S Hydrochloride

    Protein translation inhibitor.

    ≥98%
  • S9753

    Synephrine

    Endogenous alkaloid also found in citrus fruits...

    ≥98%
  • B3458

    Biopterin

    Endogenous pterin coenzyme required for release...

    ≥98%
  • L1782

    Levodopa

    Endogenous catecholamine precursor, also found ...

    ≥98%
  • T0110

    Taxane Standard Mixture

    Mixture of taxanes.

    ≥98%
  • V014457

    Valnemulin Hydrochloride

    Pleuromutilin

    ≥98%
  • C2800

    Chalcone

    Enone.

    ≥97%
  • A8812

    AWD 131-138

    GABA-A positive modulator.

    ≥99%
  • T0216

    TAE-226

    FAK inhibitor.

    ≥98%
  • C0175

    Carbetocin Acetate

    Peptide, oxytocin analog; potential OXTR agonis...

    ≥95%
  • L1044

    LCL-161

    SMAC mimetic; PXR agonist, IAP inhibitor.

    ≥99%, ≥99%ee, de
  • P6857

    Protocatechuic Acid

    Polyphenol found in many plants and foods.

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only