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Loxapine Succinate

Product ID L589921
Cas No. 27833-64-3
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $51.10 In stock
500 mg $198.50 In stock
1 g $283.50 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Loxapine is an inhibitor of dopamine receptors D2 and D4. It is a serotonin receptor antagonist and displays antipsychotic properties. It is used to treat acute agitation in patients with bipolar disorder or schizophrenia.

Product Info

Cas No.

27833-64-3

Purity

≥99%

Formula

C18H18ClN3O • C4H6O4

Formula Wt.

445.90

Chemical Name

2-chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]oxazepine succinate

IUPAC Name

butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine

Synonym

Loxapine succinate salt, Cloxazepine, Daxolin, Loxapac

Solubility

Insoluble in water. Ethanol 2 mg/mL DMSO 80 mg/mL

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

L589921 MSDS PDF

Info Sheet

L589921 Info Sheet PDF

References

de Berardis D., Fornaro M., et al. The Role of Inhaled Loxapine in the Treatment of Acute Agitation in Patients with Psychiatric Disorders: A Clinical Review. Int J Mol Sci. 18(2) (2017). PMID: 28208695.

Pollack C. Inhaled loxapine for the urgent treatment of acute agitation associated with schizophrenia or bipolar disorder. Curr Med Res Opin. 32(7):1253-60 (2016). PMID: 27121764.

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  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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