Description
Cloxacillin is a β-lactam antibiotic that displays antibacterial efficacy against a variety of species; it is especially active versus Staphylococcus. Like other β-lactam antibiotics, this compound binds penicillin binding proteins.
| Product Unit Size | Cost | Quantity | Stock | 
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Cloxacillin is a β-lactam antibiotic that displays antibacterial efficacy against a variety of species; it is especially active versus Staphylococcus. Like other β-lactam antibiotics, this compound binds penicillin binding proteins.
| Cas No. | 7081-44-9 | 
|---|---|
| Purity | ≥98% | 
| Formula | C19H17ClN3NaO5S • H2O | 
| Formula Wt. | 475.88 | 
| Chemical Name | 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3- (2-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3- dimethyl-7-oxo-, monosodium salt, (2S,5R,6R)- | 
| IUPAC Name | sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1, 2-oxazole-4-carbonyl]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | 
| Synonym | Bactopen, Cloxapen, Cloxypen, Ekvacillin, Orbenin, Methocillin-S. | 
| Melting Point | 170°C (dec) | 
| Solubility | Soluble in water, methanol, ethanol or pyridine. | 
| Appearance | White or Almost-White Crystalline Powder | 
| Store Temp | Ambient | 
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| Ship Temp | Ambient | 
| MSDS | |
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| Info Sheet | 
Sawai T, Yamaguchi A. Mechanism of beta-lactamase inhibition: differences between sulbactam and other inhibitors. Diagn Microbiol Infect Dis. 1989 Jul-Aug;12(4 Suppl):121S-129S. PMID: 2591172.
Barza M. Antimicrobial spectrum, pharmacology and therapeutic use of antibiotics. Part 2: penicillins. Am J Hosp Pharm. 1977 Jan;34(1):57-67. PMID: 318800.
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