Description
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
| Purity | ≥90% |
|---|---|
| Formula | C47H53NO15 |
| Formula Wt. | 871.92 |
| Chemical Name | D-Seco Paclitaxel |
| IUPAC Name | 1S,2S,4S,5S,7S,8S,10R,13S)-10-(acetyloxy)-4-[(acetyloxy)methyl]-1,4,5,7-tetrahydroxy-13-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.03,8]pentadec-11-en-2-yl benzoate |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.
Diterpene acid found in Pseudolarix kaempferi.<...
Thiamine, coccidiostat; thiamine transporter in...
Catalyzes hydrolysis of asparagine.
Xanthine derivative; adenosine antagonist, PDE ...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Endogenous peptide, involved in paracrine and a...
Steroidal saponin found in Tribulus, Trigonella...
Prenylated chalcone flavonoid found in Psoralea...
Polyether ionophore, autophagy inhibitor.
Hydrazine derivative, DNA alkylator; MAO inhibi...
BRD2/4/9 and CECR2 inhibitor.
Imidazoquinazoline; PDE3 inhibitor.
Isoflavone, phytoestrogen, found in soy.
Variety of flavonoid found in various plant sou...
Nitrobenzene; HPPD inhibitor.
EP4 receptor antagonist
Dihydropyridine, FIASMA; L-type Ca2+ channel bl...
Glucosinolate found in cruciferous vegetables.<...
Peptide found in amphibians.
Nucleoside (thymidine) analog.