Description
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
Purity | ≥90% |
---|---|
Formula | C47H53NO15 |
Formula Wt. | 871.92 |
Chemical Name | D-Seco Paclitaxel |
IUPAC Name | 1S,2S,4S,5S,7S,8S,10R,13S)-10-(acetyloxy)-4-[(acetyloxy)methyl]-1,4,5,7-tetrahydroxy-13-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.03,8]pentadec-11-en-2-yl benzoate |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.
NSAID; COX-1/2 inhibitor.
Thiazolidinedione; PPARγ agonist.
Isoquinoline alkaloid found in Corydalis, Phell...
Non-fluorescent halogenated A23187 analog, Ca2+...
BRD2/3/4 inhibitor.
Na+ channel blocker.
Phthalide found in celery seeds; COX-1, COX-2, ...
Thiopurine antimetabolite; PRPP amidotransferas...
Steroid 5-α-reductase inhibitor.
Alkaloid found in Corydalis and Stephania; D1/2...
Phenolic phytoalexin found in soy, grapes, and ...
Snake venom found in Crotalus durrisus terrific...
Thiazide-like diuretic; Kv7.1 and minK K+ chann...
Carotene pigment found in red and green fruits ...
Endogenous peptide, involved in stress signalin...
Endogenous peptide, involved in paracrine and a...
p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR...
Flavonoid found in Scutellaria; CDK9 inhibitor....
Dual inhibitor of p70S6K and Akt.
β-lactam; penicillin binding protein inhibitor...