Description
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
D-Seco Paclitaxel is an impurity in the production of paclitaxel.
| Purity | ≥90% |
|---|---|
| Formula | C47H53NO15 |
| Formula Wt. | 871.92 |
| Chemical Name | D-Seco Paclitaxel |
| IUPAC Name | 1S,2S,4S,5S,7S,8S,10R,13S)-10-(acetyloxy)-4-[(acetyloxy)methyl]-1,4,5,7-tetrahydroxy-13-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.03,8]pentadec-11-en-2-yl benzoate |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.
Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.
Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.
Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.
Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.
Synthetic steroid hormone; AR and ER antagonist...
Synthetic prednisolone prodrug; glucocorticoid ...
Long-chain 3-ketoacyl-CoA thiolase inhibitor, p...
Thiazolidinedione; PPARγ agonist.
Benzoylurea, insect growth regulator; chitin sy...
PKA and PDK1 inhibitor, HCN channel blocker, po...
Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adre...
B-Raf and c-Raf inhibitor.
DNA alkylator.
Selective inhibitor of LRRK2.
Pentacyclic triterpene found in the Banaba plan...
SIRT2 inhibitor.
Natural antibiotic found in Streptomyces parvul...
Phytoalexin, indole found in cruciferous vegeta...
Synthesis impurity
L-isomer of cetirizine; histamine H1 antagonist...
Synthetic non-digestible disaccharide.
For use in amino acid analysis.
Calcium channel blocker.
p110α inhibitor.