LKT Labs

Biochemicals for Life Science Research

[Des-Arg9]-Bradykinin

[Des-Arg9]-Bradykinin

Product ID B6807
Cas No. 15958-92-6
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $98.00 In stock
10 mg $168.00 In stock
25 mg $295.00 In stock
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Cas No.

15958-92-6
Purity

≥95%
Formula

C44H61N11O10
Formula Wt.

904.04
Solubility

Soluble in water (0.9 mg/mL).
Appearance

White to Off-white Powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6807 MSDS PDF
Info Sheet

B6807 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E5216

    β-Endorphin, camel

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • G1855

    Gentiopicroside

    Secoiridoid glycoside found in Gentiana and Cep...

    ≥95%
  • A4547

    Alloxan Monohydrate

    Pyrimidine, glucose analog, used to induce diab...

    ≥98%
  • C9773

    L-Cystine

    Endogenous amino acid, forms disulfide bridges ...

    ≥98%
  • V5734

    Vorinostat

    HDAC inhibitor, RNA splicing inhibitor.

    ≥98%
  • O7333

    OSI-906

    IGF-1R and InsR inhibitor.

    ≥98%
  • P465822

    Pluripotin

    Dual kinase and GTPase inhibitor.

    ≥98%
  • V0269

    Vardenafil Dihydrochloride

    PDE5 inhibitor.

    ≥99%
  • H0142

    Haloperidol

    Butyrophenone; σ2 agonist, α1-adrenergic, D2,...

    ≥95%
  • E7657

    Etoposide

    Podophyllotoxin derivative; topoisomerase II in...

    ≥98%
  • M184770

    4-O-Methylhonokiol

    Found in Magnolia officinalis.

    ≥98%
  • P691320

    PRI-724

    Wnt/beta-catenin/CBP inhibitor

    ≥98%
  • A4777

    Altiratinib

    c-MET, Tie-2, VEGFR inhibitor.

    ≥98%
  • E9418

    Exendin 3 (9-39)

    Peptide, GLP-1 analog found in Heloderma; GLP-1...

    ≥95%
  • A9912

    AZD-7762 Hydrochloride

    CHK1 inhibitor.

    ≥98%
  • R4132

    RKI-1447

    ROCK1/2 inhibitor.

    ≥98%
  • A5234

    Amisulpride

    5-HT7 and D2/3 antagonist.

    ≥98%
  • C1609

    Cecropin B

    Antimicrobial peptide found in Hyalophora cecro...

    ≥95%
  • A0776

    ABT-199

    BH3 mimetic; Bcl-2 inhibitor.

    ≥99%
  • L9701

    LY-450139

    GHS-R1a agonist, γ-secretase inhibitor.

    ≥98%