LKT Labs

Biochemicals for Life Science Research

[Des-Arg9]-Bradykinin

[Des-Arg9]-Bradykinin

Product ID B6807
Cas No. 15958-92-6
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $98.40 In stock
10 mg $167.80 In stock
25 mg $294.60 In stock
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Cas No.

15958-92-6
Purity

≥95%
Formula

C44H61N11O10
Formula Wt.

904.04
Solubility

Soluble in water (0.9 mg/mL).
Appearance

White to Off-white Powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6807 MSDS PDF
Info Sheet

B6807 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0110

    Taxane Standard Mixture

    Mixture of taxanes.

    ≥98%
  • G0245

    Gallocatechin Gallate

    Polyphenol found in Camilla sinensis; HIV integ...

    ≥98%
  • T3197

    L-Thyroxine Sodium Pentahydrate

    Endogenous thyroid hormone T4.

    ≥97%
  • A971334

    Azilsartan

    Sartan

    ≥98%
  • A1218

    Adefovir Dipivoxil

    Acyclic nucleotide (adenosine) analog, adefovir...

    ≥98%
  • M3321

    Mifepristone

    Synthetic steroid, contraceptive; PR and glucoc...

    ≥98%
  • R6052

    Recombinant Mycoplasma Pneumonia Antigen

    Pneumonia antigen
  • N3225

    Nigericin Sodium

    Polyether cationic ionophore.

    ≥98%
  • A5280

    Angiotensin II (3-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • T0097

    10-Deacetyltaxol B

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • S771337

    STING Agonist-1

    Indirect activator of STING signaling

    ≥98%
  • T3357

    Tioconazole

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • A4438

    Allatostatin I

    Neuropeptide found in insects; juvenile hormone...

    ≥95%
  • S822687

    Surfactin

    Amphiphilic properties

    ≥90% mixed isomers
  • T1952

    Tenuazonic Acid Copper Salt

    Mycotoxin produced by Alternaria; photosynthesi...

    ≥98%
  • K1978

    Ketorolac Tromethamine

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • E846182

    Everolimus EP Impurity E

    Impurity of everolimus

    ≥80%
  • C000082

    C-82

    beta-catenin inhibitor

    ≥99%
  • H9611

    Hydrocortisone

    Endogenous steroid hormone involved in stress s...

    ≥98%
  • V3252

    Vinorelbine Ditartrate

    Semi-synthetic vinca alkaloid from Catharanthus...

    ≥98%