LKT Labs

Biochemicals for Life Science Research

Dexamethasone Acetate Monohydrate

Dexamethasone Acetate Monohydrate

Product ID D1694
Cas No. 55812-90-3
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $75.00 In stock
500 mg $206.00 In stock
1 g $365.30 In stock
Bulk Quote

Quicklinks

Description

Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration and maturation of macrophages. Dexamethasone may also display anti-asthma benefit as well, through the upregulation of PTEN expression. Additionally, dexamethasone is often used in combination with other chemotherapeutics in the treatment of multiple myeloma.

Product Info

Cas No.

55812-90-3
Purity

≥98%
Formula

C24H31FO6 • H2O
Formula Wt.

452.52
Chemical Name

(11β, 16α)-9-Fluoro-11,17,21-trihydroxy-16- methylpregna-1,4-diene-3,20-dione 21-acetate
IUPAC Name

[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13, 16-trimethyl-3-oxo-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;hydrate
Synonym

Dexamethasone 21-Acetate, Decadronal, Dectancyl, Dexacortisyl
Melting Point

229-231°C
Appearance

White crystalline powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

D1694 MSDS PDF
Info Sheet

D1694 Info Sheet PDF

References

Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C760001

    CT-7001

    CDK7 inhibitor

    ≥99%
  • T5611

    δ-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • W0270

    (±)-Warfarin Sodium Clathrate

    Coumarin; VKORC1 inhibitor.

    ≥98%
  • G2868

    Ghrelin, human

    Endogenous peptide hormone, involved in feeding...

    ≥98%
  • A6970

    Artemether

    Sesquiterpene lactone derived from Artemesia.

    ≥98%
  • T0120

    2′,7-bis(triethylsilyl)taxol

    Synthesis intermediate

    ≥98%
  • P2997

    Phytic Acid, 40-50 wt% aqueous solution

    Saturated cyclic acid used to store phosphorus ...

    ≥40%
  • N3323

    Nifuratel

    Nitrofuran derivative.

    ≥99%
  • I5072

    Imazalil

    Triazole; 14-α demethylase and aromatase inhib...

    ≥95%, titration; ≥70%, HPLC
  • B030964

    BAY-1816032

    BUB1 inhibitor.

    ≥99%
  • H0003

    H89

    PKA inhibitor, potential ROCK, S6K1, MSK1, PKB ...

    ≥98%
  • C0378

    Catharanthine Tartrate

    Alkaloid found in Catharanthus, precursor in sy...

    ≥97%
  • F3354

    Finasteride

    Steroid 5-α-reductase inhibitor.

    ≥98%
  • G7241

    GSK-461364

    PLK1 inhibitor.

    ≥99%
  • V3345

    Vildagliptin

    DPP4 inhibitor.

    ≥98%
  • M5876

    Motesanib

    VEGFR1/2/3, PDGFR, c-Kit, RET inhibitor.

    ≥98%
  • C5768

    Corazonin

    Neuropeptide found in insects.

    ≥95%
  • V182705

    Verubecestat

    BACE1 inhibitor

    ≥98%
  • A6058

    Apoptosis Activator 2

    Apoptosis inducing agent.

    ≥98%
  • B030967

    BAY-1895344

    ATR inhibitor.

    ≥99%