Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
| Product Unit Size | Cost | Quantity | Stock |
|---|
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
| Cas No. | 125-84-8 |
|---|---|
| Purity | ≥98% |
| Formula | C13H16N2O2 |
| Formula Wt. | 232.28 |
| Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
| IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
| Synonym | Aminoglutethimide, Cytadren, Elipten, Orimeten |
| Melting Point | 149-150°C |
| Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
| Appearance | White Crystalline Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
Targets nuclear factor kappa B activation.
Peptide, binds heparin.
Endogenous peptide, involved in vascular contra...
Imidazole; HMG-CoA reductase, 14-α demethylase...
Optically active isomer of ibuprofen, NSAID; CO...
Protease inhibitor.
Dihydropyridine; L-type Ca2+ channel blocker.
Mycotoxin metabolite
BHA derivative; potential Ca2+ ATPase inhibitor...
Triterpenoid
Pt-based DNA cross-linker.
K+-sparing diuretic; ENaC and acid-sensing ion ...
FAK inhibitor.
Actinomycin derivative used to study apoptosis ...
Inhibitor of CDK.
Sesquiterpene lactone derived from Artemesia; m...
Triterpene aglycone originally found in Centell...
Taxane synthesis intermediate.
SIRT1/2 inhibitor, indirect p53 activator.
Third generation macrocyclic ALK inhibitor.