Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
| Product Unit Size | Cost | Quantity | Stock |
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D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
| Cas No. | 125-84-8 |
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| Purity | ≥98% |
| Formula | C13H16N2O2 |
| Formula Wt. | 232.28 |
| Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
| IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
| Synonym | Aminoglutethimide, Cytadren, Elipten, Orimeten |
| Melting Point | 149-150°C |
| Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
| Appearance | White Crystalline Powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
Flavonoid found in various plant sources; DAT a...
DNA alkylator.
Lignan found in Magnolia; GABA-A potentiator.
Terpene lactone found in Ginkgo; GlyR antagonis...
InsR and IGF-1R inhibitor.
FIASMA, mAChR, 5-HT2/3/6/7, α1/2-adrenergic an...
Endogenous hormone neurotransmitter, involved i...
TGF-β1 inhibitor.
Triterpenoid
PKC and PKG inhibitor.
H+/K+ ATPase inhibitor.
PDE3 inhibitor.
CDK1/2 inhibitor.
Phallotoxin found in Amanita phalloides; microt...
Aromatic 1,3-diketone acetylacetone derivative ...
Triterpene; potential tyrosinase inhibitor.
Inhibitor of Akt.
Water-soluble cortisol derivative; glucocortico...
Peptide found in insects.
T-type Ca2+ and voltage-gated Na+ channel block...