Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
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D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
| Cas No. | 125-84-8 |
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| Purity | ≥98% |
| Formula | C13H16N2O2 |
| Formula Wt. | 232.28 |
| Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
| IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
| Synonym | Aminoglutethimide, Cytadren, Elipten, Orimeten |
| Melting Point | 149-150°C |
| Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
| Appearance | White Crystalline Powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
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