Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
Product Unit Size | Cost | Quantity | Stock |
---|
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
Cas No. | 125-84-8 |
---|---|
Purity | ≥98% |
Formula | C13H16N2O2 |
Formula Wt. | 232.28 |
Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
Synonym | Aminoglutethimide, Cytadren, Elipten, Orimeten |
Melting Point | 149-150°C |
Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
Appearance | White Crystalline Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
Mycotoxin produced by Alternaria; photosynthesi...
Found in Buxus; hERG K+ channel inhibitor.
Avermectin; glu-gated Cl- channel activator, Gl...
5-α-Reductase inhibitor.
Building block
Natural anthraquinone derivative
Macrolide antibiotic
Alkaloid compound originally found in Corydalis...
Nitrogen mustard, DNA alkylator.
Promotes Aβ clearance.
SGLT2 inhibitor
SK K+ channel blocker, EGFR inhibitor.
D2/3 antagonist, hERG K+ channel blocker.
Nav1.8 Na+ channel blocker, potential Nav1.5 Na...
Bone deterioration inhibitor, potential CaR ago...
Diarylether; bacterial ENR binder, fatty acid s...
Glycolic acid ester prodrug of indomethacin, NS...
Dihydropyridine, FIASMA; L-type Ca2+ channel bl...
Polymixin, antimicrobial peptide, induces forma...