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Dynasore

Dynasore

Product ID D9752
Cas No. 304448-55-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $84.40 In stock
25 mg $312.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dynasore is an inhibitor of dynamin, a protein involved in membrane fission during endocytosis; it displays anti-resorptive, anti-osteoporotic, and antiviral activities. Dynasore inhibits bone resorption by preventing actin ring formation in osteoclasts. This compound also suppresses viral entry and infection of herpes simplex virus (HSV). Dynasore also inhibits transport of viral proteins from the nucleus to the cytosol by preventing co-localization of VP5 and dynamin.

Product Info

Cas No.

304448-55-3

Purity

≥98%

Formula

C18H14N2O4

Formula Wt.

322.32

IUPAC Name

N'-[(E)-(3,4-Dihydroxyphenyl)methylene]-3-hydroxy-2-naphthohydrazide

Solubility

DMSO: ≥10 mg/mL H2O: insoluble

Appearance

Light yellow solid

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D9752 MSDS PDF

Info Sheet

D9752 Info Sheet PDF

References

Mues MB, Cheshenko N, Wilson DW, et al. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015 Jul 1;89(13):6673-84. PMID: 25878109.

Thirukonda GJ, Uehara S, Nakayama T, et al. The dynamin inhibitor dynasore inhibits bone resorption by rapidly disrupting actin rings of osteoclasts. J Bone Miner Metab. 2015 Jun 11. [Epub ahead of print]. PMID: 26063501.

Preta G, Cronin JG, Sheldon IM. Dynasore - not just a dynamin inhibitor. Cell Commun Signal. 2015 Apr 10;13:24. PMID: 25889964.

Custom Order

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