LKT Labs

Biochemicals for Life Science Research

Enalaprilat Dihydrate

Enalaprilat Dihydrate

Product ID E5200
Cas No. 84680-54-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $172.00 In stock
50 mg $745.00 In stock
100 mg $1,374.00 In stock
Bulk Quote

Quicklinks

Description

Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits antihypertensive activity. Enalapril prevents and reverses renovascular hypertension-induced smooth muscle hypertrophy, collagen deposition, carotid media thickness growth, and other parameters of arterial remodeling. Additionally, enalapril improves endothelial function in migraine sufferers by increasing levels of NO.

Product Info

Cas No.

84680-54-6
Purity

≥98%
Formula

C18H24N2O5 • 2H2O
Formula Wt.

384.42
Chemical Name

N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate

IUPAC Name

(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid;dihydrate

Synonym

Enalaprilic acid, Vasotec IV
Melting Point

148-151°C
Solubility

Slightly soluble in water (14 mg/mL at 60 oC) DMSO (64 mg/mL), methanol (14 mg/mL).

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E5200 MSDS PDF
Info Sheet

E5200 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • V0144

    n-Valeric Acid

    GHB/GABA analog found in Valeriana officinalis;...

    ≥99%
  • V1872

    Vesicular Stomatitis Virus Peptide

    Peptide fragment of VSV; LDLR agonist.

    ≥95%
  • A5378

    Antimycin A

    Oxidative phosphorylation inhibitor.
  • V3326

    Virginiamycin S1

    Macrolide antibiotic; peptidyl transferase inhi...

    ≥99%
  • M0009

    Macitentan

    ET-A/B antagonist.

    ≥99%
  • U682040

    URB597

    FAAH inhibitor.

    ≥98%
  • D1631

    Dehydrocorydaline

    Alkaloid compound originally found in Corydalis...

    ≥95%
  • I0482

    S-(+)-Ibuprofen

    Optically active isomer of ibuprofen, NSAID; CO...

    ≥98%
  • P6959

    Prothionamide

    Nicotinic acid derivative; InhA inhibitor.

    ≥98%
  • A7577

    Astilbin

    Flavonoid found in various plant sources.

    ≥99%
  • P3462

    Piperacillin

    β-lactam; penicillin binding protein inhibitor...

    ≥95%
  • A7071

    Atriopeptin II, rat/rabbit/mouse

    ANP analog, cardiomodulatory peptide; NPR-A ago...

    ≥95%
  • C0160

    Canrenone

    Metabolite of spironolactone; Na+/K+ ATPase par...

    ≥98%
  • M3232

    Methylisoindigotin

    Indirubin derivative.

    ≥98%
  • A0776

    ABT-199

    BH3 mimetic; Bcl-2 inhibitor.

    ≥99%
  • C6818

    Crenolanib

    FLT3, PDGFR inhibitor.

    ≥98%
  • S336507

    Simufilam Dihydrochloride

    Unlikely to reverse Alzheimer’s

    ≥98%
  • V182705

    Verubecestat

    BACE1 inhibitor

    ≥98%
  • X4424

    XL-765

    PI3K and mTOR inhibitor.

    ≥98%
  • P6855

    (±)-S-Propyl-L-cysteine-S-oxide

    Organosulfur found in Allium; analog of alliin....

    ≥98%