LKT Labs

Biochemicals for Life Science Research

Enalaprilat Dihydrate

Enalaprilat Dihydrate

Product ID E5200
Cas No. 84680-54-6
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $172.00 In stock
50 mg $745.00 In stock
100 mg $1,374.00 In stock
Bulk Quote

Quicklinks

Description

Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that is clinically used to treat hypertension, heart failure, and diabetic nephropathy. Enalapril exhibits antihypertensive activity. Enalapril prevents and reverses renovascular hypertension-induced smooth muscle hypertrophy, collagen deposition, carotid media thickness growth, and other parameters of arterial remodeling. Additionally, enalapril improves endothelial function in migraine sufferers by increasing levels of NO.

Product Info

Cas No.

84680-54-6
Purity

≥98%
Formula

C18H24N2O5 • 2H2O
Formula Wt.

384.42
Chemical Name

N-[(1S)-Carboxy- 3-phenylpropyl]-L-alanyl-L-proline dihydrate

IUPAC Name

(2S)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid;dihydrate

Synonym

Enalaprilic acid, Vasotec IV
Melting Point

148-151°C
Solubility

Slightly soluble in water (14 mg/mL at 60 oC) DMSO (64 mg/mL), methanol (14 mg/mL).

Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

E5200 MSDS PDF
Info Sheet

E5200 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Bilan VP, Salah EM, Bastacky S, et al. Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats. J Endocrinol. 2011 Sep;210(3):293-308. PMID: 21680617.

Javanmard SH, Sonbolestan SA, Heshmat-Ghahdarijani K, et al. Enalapril improves endothelial function in patients with migraine: A randomized, double-blind, placebo-controlled trial. J Res Med Sci. 2011 Jan;16(1):26-32. PMID: 21448379.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A4806

    Ambroxol Hydrochloride

    Expectorant.

    ≥98%
  • R0154

    Ranolazine Dihydrochloride

    Nav1.7 and Nav1.8 N1+ channel blocker.

    ≥98%
  • A4443

    L-(+)-Alliin

    Optically active cysteine derivative found in A...

    ≥98%
  • A9914

    AZD-8055

    mTOR inhibitor.

    ≥98%
  • T1010

    7-Acetyl Paclitaxel

    Synthesis impurity

    ≥98%
  • S8243

    Sulbactam Sodium

    β-lactamase inhibitor.

    ≥98%
  • I530280

    INH1

    Hec1/Nek2 mitotic pathway inhibitor

    ≥98%
  • F8048

    Fumagillin

    Produced by Aspergillus; type 2 methionine amin...

    ≥98%
  • P8270

    Purvalanol A

    Purine derivative; CDK inhibitor.

    ≥98%
  • C9778

    Cytarabine

    Pyrimidine nucleoside (cytidine) analog; DNA ch...

    ≥98%
  • B1853

    1,4-Benzoquinone

    Precursor in the synthesis of hydroquinone, ant...

    ≥98%
  • E5220

    Enfuvirtide (T-20)

    Synthetic peptide derived from HIV-1; viral fus...

    ≥95%
  • R1627

    Regorafenib Anhydrous

    Multikinase inhibitor.

    ≥99%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • L0360

    Lapatinib Ditosylate Monohydrate

    EGFR inhibitor.

    ≥99%
  • M1564

    S-Methyl-L-cysteine

    Antioxidant found in Brassicaceae family plants...

    ≥99%
  • A745817

    Asunaprevir

    Antiviral againt SARS-CoV-2

    ≥98%
  • I7341

    Isoniazid

    Nicotinic acid derivative; InhA inhibitor.

    ≥98%
  • R1878

    Retinyl Acetate

    Vitamin A derivative, acetate ester of retinol....

    ≥98%
  • D364086

    Decernotinib

    JAK3 inhibitor.

    ≥99%