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Epirubicin Hydrochloride

Epirubicin Hydrochloride

Product ID E6235
Cas No. 56390-09-1
Purity ≥90%
Product Unit SizeCostQuantityStock
1 mg $71.50 In stock
5 mg $142.90 In stock
10 mg $245.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Epirubicin is an anthracycline that exhibits anticancer chemotherapeutic activity; it is an isomer of doxorubicin. Epirubicin acts as a DNA intercalator and topoisomerase II inhibitor, inhibiting DNA and RNA synthesis. This compound also increases levels of ROS. Epirubicin is clinically used to treat breast cancer.

Product Info

Cas No.

56390-09-1

Purity

≥90%

Formula

C27H29NO11 • HCl

Formula Wt.

579.99

Chemical Name

10-((3-amino-2,3,6-trideoxy-beta-L-arabino- hexopyranosyl)oxy)-7,8,9,10-tetrahydro- 6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy- (8S-cis)-5,12-naphthacenedione hydrochloride

IUPAC Name

(7S,9S)-7-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9, 11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5, 12-dione;hydrochloride

Synonym

4'-Epiadriamycin, Epiadriamycin, Ridorubicin, Ellence, Farmorubicin, Pharmorubicin

Melting Point

185°C (dec.)

Solubility

Soluble in water, methanol. Insoluble in acetone.

Appearance

Orange-red powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

E6235 MSDS PDF

Info Sheet

E6235 Info Sheet PDF

References

Monteiro LJ, Khongkow P, Kongsema M, et al. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment. Oncogene. 2013 Sep 26;32(39):4634-45. PMID: 23108394.

Conte PF, Gennari A, Landucci E, et al. Role of epirubicin in advanced breast cancer. Clin Breast Cancer. 2000 Sep;1 Suppl 1:S46-51. PMID: 11970749.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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