Description
Eptifibatide is an inhibitor of glycoprotein GP IIb/IIIa that exhibits antiplatelet/antithrombotic activity. Eptifibatide inhibits fibrinogen-mediated platelet aggregation and is clinically used to treat acute coronary syndrome.
Eptifibatide
Product ID E6376
Cas No. 188627-80-7
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 188627-80-7 |
|---|---|
| Purity | ≥98% |
| Formula | C35H49N11O9S2 |
| Formula Wt. | 832.4 |
| Chemical Name | N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-L-Cysteinamide, cyclic (1-6)-disulfide |
| IUPAC Name | 2-[20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3- ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13, 21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid |
| Synonym | Integrilin |
| Solubility | Soluble in water (5 mg/mL), methanol, DMSO (10 mg/mL), ethanol (5 mg/mL), DMF (30 mg/mL). |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Angiolillo DJ. The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. Drugs. 2012 Nov 12;72(16):2087-116. PMID: 23083110.
Gurbel PA, Galbut B, Bliden KP, et al. Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy). J Thromb Thrombolysis. 2002 Dec;14(3):213-9. PMID: 12913401.