• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Fidaxomicin

Fidaxomicin

Product ID F285081
Cas No. 873857-62-6
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $77.80 In stock
100 mg $220.60 In stock
250 mg $473.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fidaxomicin is a macrocyclic antibiotic, isolated from actinomycete Dactylosporangium aurantiacum. Fidaxomicin is an RNA polymerase inhibitor that has a narrow antibiotic activity spectrum and is not readily absorbed into the blood circulatory system. This anti-bacterial agent is almost Clostridium difficile specific in the colon, and has minimal effect to the intestinal microbial flora.

Product Info

Cas No.

873857-62-6

Purity

≥98%

Formula

C52H74Cl2O18

Formula Wt.

1058.05

Chemical Name

 [(2R,3S,4S,5S,6R)-6-[[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-(2-methylpropanoyloxy)oxan-2-yl]oxy-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy]-4-hydroxy-5-methoxy-2-methyloxan-3-yl] 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate

IUPAC Name

 [(2R,3S,4S,5S,6R)-6-[[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-(2-methylpropanoyloxy)oxan-2-yl]oxy-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy]-4-hydroxy-5-methoxy-2-methyloxan-3-yl] 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate

Synonym

Clostomicin B1, Dificid, Dificlir, lipiarmicin lipiarmycin, lipiarmycin A3, tiacumicin B.

Solubility

Insoluble in water, soluble in CHCl3(10 mg/ml), methanol(10 mg/ml), DMSO(1mg/ml).

Appearance

White to offwhite powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

F285081 MSDS PDF

Info Sheet

F285081 Info Sheet PDF

References

Poxton IR. Fidaxomicin: a new macrocyclic, RNA polymerase-inhibiting antibiotic for the treatment of Clostridium difficile infections. Future Microbiol. 2010 ;5(4):539-48 doi: 10.2217/fmb.10.20.PMID: 20353295 Review.

Yuan J, Yu J, Huang Y, et al. Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus. BMC Med. 2020 Jul 31;18(1):204. PMID: 32731873.

Koon H, Wang J, Mussatto, C, et al. Fidaxomicin and OP-1118 inhibit Clostridium difficile toxin A- and B- mediated inflammatory responses via inhibition of NF-kB activity. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01513-17. PMID: 29038278.

Dailler D, Dorst A, Schafle D, et al. Novel fidaxomicin antibiotics through site-selective catalysis. Communications Chamistry. 2021. 4:59.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D564090

    7-epi-Docetaxel

    Docetaxel impurity

    ≥95%
  • K0054

    Kanamycin B

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • C3214

    CID-797718

    Potential PKD binding agent.

    ≥99%
  • O4917

    Omeprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • S1058

    Scopolamine N-butylbromide

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%
  • T3461

    Tiplaxtinin

    PAI-1 inhibitor.

    ≥98%
  • P0001

    P1 Peptide

    Octapeptide, prevents EGFR-PLCγ association.

    ≥95%
  • C8502

    CV-70

    1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...

    ≥70%
  • A6971

    ARRY-162

    MEK1/2 and ERK inhibitor.

    ≥99%
  • S7061

    SRPIN340

    SRPK1 inhibitor.

    ≥98%
  • C5680

    Coumestrol

    Phytoestrogen found in various plant sources; E...

    ≥97%
  • N3301

    Niacin

    Vitamin B, required for formation of NAD and NA...

    ≥98%
  • I0416

    Iberin

    Isothiocyanate found in cruciferous vegetables,...

    ≥97%
  • A064766

    ABT 639

    T-type calcium channel blocker

    ≥99%
  • G4434

    Gliotoxin

    Toxin produced by Aspergillus.

    ≥98%
  • A046189

    Abexinostat

    Primarily targets HDAC1

    ≥98%
  • A5170

    Amrinone

    Pyridine; PDE3 inhibitor.

    ≥98%
  • A0248

    BAM-12P

    Peptide, cleavage product of proenkephalin; κO...

    ≥95%
  • T0093

    2′-Acetyltaxol

    Taxane synthesis intermediate.

    ≥98%
  • C2947

    Chlorpromazine Hydrochloride

    Phenothiazine, FIASMA; D1/2/3/4, 5-HT1/2, M1/2 ...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only