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Finasteride

Finasteride

Product ID F3354
Cas No. 98319-26-7
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $141.80 In stock
500 mg $529.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Finasteride is an inhibitor of steroid 5-α-reductase that decreases metabolism of testosterone, decreasing cell proliferation and fluid production in the prostate; it is clinically used to treat benign prostatic hyperplasia (BPH) and male pattern baldness. Finasteride also exhibits antifungal and anticancer chemotherapeutic activities. Finasteride inhibits growth of Candida. Additionally, finasteride suppresses regrowth of regressed prostate tumors and inhibits cell proliferation in vivo and in vitro in short term application models.

Product Info

Cas No.

98319-26-7

Purity

≥98%

Formula

C23H36N2O2

Formula Wt.

372.54

Chemical Name

(5α,17β)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost- 1-ene-17-carboxamide

IUPAC Name

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3, 3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

Synonym

Finastid, Propecia, Proscar, Prostide

Melting Point

252-254°C °r 257°C

Solubility

Soluble in chloroform. DMSO, ethanol and methanol. Slighly soluble in water.

Appearance

White/off-white Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F3354 MSDS PDF

Info Sheet

F3354 Info Sheet PDF

References

Chavez-Dozal AA, Lown L, Jahng M, et al. An in vitro analysis of finasteride activity against Candida albicans urinary biofilm formation and filamentation. Antimicrob Agents Chemother. 2014 Jul 21. [Epub ahead of print]. PMID: 25049253.

Masoodi KZ, Ramos Garcia R, Pascal LE, et al. 5α-reductase inhibition suppresses testosterone-induced initial regrowth of regressed xenograft prostate tumors in animal models. Endocrinology. 2013 Jul;154(7):2296-307. PMID: 23671262.

Zager MG, Barton HA. A multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenance. PLoS One. 2012;7(9):e44359. PMID: 22970204.

Custom Order

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