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Florfenicol

Florfenicol

Product ID F4556
Cas No. 73231-34-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $110.30 In stock
5 g $275.60 In stock
10 g $463.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Florfenicol is a synthetic fluorinated analog of thiamphenicol that exhibits antibiotic activity in livestock. Florfenicol acts as an antibacterial against Shigella, Escherichia, Klebsiella, Enterobacter, and Haemophilus. Florfenicol binds 23S rRNA on the bacterial 50S ribosome, inhibiting translation.

Product Info

Cas No.

73231-34-2

Purity

≥98%

Formula

C12H14Cl2FNO4S

Formula Wt.

358.21

Chemical Name

2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-methylsulfonyl)-phenyl]ethyl]acetamide

IUPAC Name

2,2-dichloro-N-[(1R, 2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide

Synonym

Fluorothiamphenicol, Aquafen

Melting Point

153-154°C

Solubility

Acetone, DMF. Slightly soluble in water (1.3 mg/ml).

Appearance

White or off-white Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4556 MSDS PDF

Info Sheet

F4556 Info Sheet PDF

References

Kehrenberg C, Schwarz S, Jacobsen L, et al. A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Mol Microbiol. 2005 Aug;57(4):1064-73. PMID: 16091044.

Syriopoulou VP, Harding AL, Goldmann DA, et al. In vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol. Antimicrob Agents Chemother. 1981 Feb;19(2):294-7. PMID: 6957162.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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