LKT Labs

Biochemicals for Life Science Research

Flumequine Sodium

Flumequine Sodium

Product ID F4881
Cas No. 42835-68-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $56.40 In stock
5 g $180.00 In stock
25 g $561.40 In stock
Bulk Quote

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Description

Flumequine is a fluoroquinolone antibiotic commonly used in veterinary medicine. Flumequine exhibits antibacterial efficacy through the inhibition of bacterial DNA gyrase. This compound also displays other activity, inhibiting GABA-A receptors in the ileum, and displays cancer-related activity in the liver, although reports conflict as to whether flumequine is chemopreventive or carcinogenic. Additionally, this compound was previously explored as a treatment for urinary tract infection in humans, although is not currently used in that manner.

Product Info

Cas No.

42835-68-7
Purity

≥98%
Formula

C14H11FNNaO3
Formula Wt.

283.23
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

F4881 MSDS PDF
Info Sheet

F4881 Info Sheet PDF

References

Kuroiwa Y, Umemura T, Nishikawa A, et al. Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice. Arch Toxicol. 2007 Jan;81(1):63-9. PMID: 16802149.

Vik-Mo FT, Bergh O, Samuelsen OB. Efficacy of orally administered flumequine in the treatment of vibriosis caused by Listonella anguillarum in atlantic cod Gadus morhua. Dis Aquat Organ. 2005 Nov 9;67(1-2):87-92. PMID: 16385813.

Koutsoviti-Papadopoulou M, Kounenis G, Elezoglou V. Inhibitory effect of flumequine, enoxacin and norfloxacin on the GABA-induced contractile effect on the guinea pig ileum. Gen Pharmacol. 1995 Oct;26(6):1391-5. PMID: 7590136.

Schena FP, Gesualdo L, Caracciolo G. A multicentre study of flumequine in the treatment of urinary tract infections. J Antimicrob Chemother. 1988 Jan;21(1):101-6. PMID: 3356617.

Smith JT. The mode of action of 4-quinolones and possible mechanisms of resistance. J Antimicrob Chemother. 1986 Nov;18 Suppl D:21-9. PMID: 3542946.

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