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Flunisolide is a corticosteroid commonly used in the treatment of allergic rhinitis. It is an analog of budesonide and has been predicted to have a positive effect in the treatment of SARS-CoV-2 viral infections. It has also been shown to successfully inhibit HIV viral replication in vitro.
| Cas No. | 3385-03-3 |
|---|---|
| Purity | ≥90% |
| Formula | C24H31FO6 |
| Formula Wt. | 434.5 |
| IUPAC Name | (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| Synonym | 6 alpha-fluorodihydroxy-16 alpha,17 alpha-isopropylidenedioxy-1,4-pregnadiene-3,20- dione; Aerobid; Rhinalar; Synaclyn |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| Info Sheet |
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Reinero C, Brownlee L, Decile K, et al. Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats. J Vet Intern Med. 2006 Jan-Feb;20(1):57-64. PMID: 16496924.
Nunnari G, Sanfilippo C, Castrogiovanni P, et al. Network perturbation analysis in human bronchial epithelial cells following SARS-CoV2 infection. Exp Cell Res. 2020 Oct 15;395(2):112204. PMID: 32735892.
Wagstaff K, Headey S, Telwatte S, et al. Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import. Cell Microbiol. 2019 Jan;21(1):e12953. PMID: 30216959.