Description
Gatifloxacin is a fluoroquinolone antibiotic that inhibits DNA gyrase. Gatifloxacin exhibits antibacterial efficacy against Mycobacterium and Streptococcus, treating tuberculosis and pneumonia.
Gatifloxacin Sesquihydrate
Product ID G0278
Cas No. 180200-66-2
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 180200-66-2 |
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| Purity | ≥98% |
| Formula | (C19H22FN3O4)2 • (H2O)3 |
| Formula Wt. | 402.42 |
| Chemical Name | 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
| IUPAC Name | 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4- oxoquinoline-3-carboxylic acid |
| Synonym | Tequin |
| Melting Point | 162°C |
| Solubility | Soluble in water (40-60 mg/mL) at a pH of 2 to 5. |
| Appearance | White Crystal Powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Pantel A, Petrella S, Veziris N, et al. Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. PMID: 22290942.
Croisier D, Etienne M, Piroth L, et al. In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother. 2004 Sep;54(3):640-7. PMID: 15317743.