• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ginsenoside Rb1

Ginsenoside Rb1

Product ID G3454
Cas No. 41753-43-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $93.80 In stock
5 mg $260.00 In stock
10 mg $439.40 In stock
25 mg $859.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ginsenoside Rb1 is a triterpene saponin originally found in species of Panax that exhibits antioxidative, anti-inflammatory, neuroprotective, orexigenic, and stimulatory activities. In animal models, ginsenoside Rb1 increases motor activity, food intake, and skeletal muscle ATP content, improving energy metabolism. Ginsenoside Rb1 also downregulates expression of toll-like receptor 4 (TLR4) and TNF-α in animal models of sepsis, protecting against liver and lung damage. Additionally, ginsenoside Rb1 inhibits glucose-induced neurotoxicity by preventing GSK-3β-stimulated CHOP induction. This compound also activates Nrf2 and increases expression of heme oxygenase 1 (HO-1), suppressing oxidative stress in vitro.

Product Info

Cas No.

41753-43-9

Purity

≥98%

Formula

C54H92O23

Formula Wt.

1109.29

IUPAC Name

2-[[6-[2-[3-[4,5-dihydroxy-6-(hydroxymethyl)-3-[3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-12-hydroxy-4,4, 8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2- yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4, 5-triol

Synonym

Arasaponin E1, Gypenoside III, Sanchinoside E1

Solubility

Soluble in water. Soluble in methanol or ethanol

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

G3454 MSDS PDF

Info Sheet

G3454 Info Sheet PDF

References

Tan SJ, Li N, Zhou F, et al. Ginsenoside Rb1 improves energy metabolism in the skeletal muscle of an animal model of postoperative fatigue syndrome. J Surg Res. 2014 May 2. [Epub ahead of print]. PMID: 24881470.

Wu LL, Jia BH, Sun J, et al. Protective effects of ginsenoside Rb1 on septic rats and its mechanism. Biomed Environ Sci. 2014 Apr;27(4):300-3. PMID: 24758759.

Liu D, Zhang H, Gu W, et al. Ginsenoside Rb1 protects hippocampal neurons from high glucose-induced neurotoxicity by inhibiting GSK3β-mediated CHOP induction. Mol Med Rep. 2014 Apr;9(4):1434-8. PMID: 24535619.

Ni N, Liu Q, Ren H, et al. Ginsenoside Rb1 protects rat neural progenitor cells against oxidative injury. Molecules. 2014 Mar 7;19(3):3012-24. PMID: 24662068.

Xiong Y, Shen L, Liu KJ, et al. Antiobesity and antihyperglycemic effects of ginsenoside Rb1 in rats. Diabetes. 2010 Oct;59(10):2505-2512. PMID: 20682695.

Shen L, Xiong Y, Wang DQ, et al. Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats. J Lipid Res. 2013 May;54(5):1430-1438. PMID: 23434611.

Lee JS, Song JH, Sohn NW, Shin JW. Inhibitory effects of ginsenoside Rb1 on neuroinflammation fl=ollowing systemic lipopolysaccharide treatment in mice. Phytother Res. 2013 Sep;27(9):1270-1276. PMID: 23042638.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S1060

    Small Cardioactive Peptide A

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • P200600

    PF-06873600

    CDK2/4/6 inhibitor

    ≥98%
  • L0360

    Lapatinib Ditosylate Monohydrate

    EGFR inhibitor.

    ≥99%
  • A454470

    L-Allylglycine

    Inhibitor of glutamic acid decarboxylase (GAD)....

    ≥98%
  • I5992

    IOX2

    Prolyl hydroxylase inhibitor.

    ≥98%
  • N3323

    Nifuratel

    Nitrofuran derivative.

    ≥99%
  • A5059

    Amoxapine

    5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenerg...

    ≥98%
  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • P2100

    PF-06447475

    LRRK2 inhibitor.

    ≥98%
  • G0250

    cGAMP Disodium [STING Ligand]

    Cyclic dinucleotide that detects cytosolic DNA ...

    ≥98%
  • V1871

    Veratridine

    Binds to neurotoxin receptor site 2 on voltage-gat...
    ≥98%
  • T0097

    10-Deacetyltaxol B

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • A6132

    Apicidin

    Cyclic tetrapeptide; HDAC inhibitor.

    ≥98%
  • B1545

    Benzalkonium Bromide

    Quaternary ammonium cationic surfactant, dissoc...

    ≥95%
  • C5680

    Coumestrol

    Phytoestrogen found in various plant sources; E...

    ≥97%
  • T0116

    2″,3″-Dihydrocephalomannine

    Cephalomannine derivative found in Taxus; poten...

    ≥96%
  • T0002

    T2 Toxin

    Trichothecene mycotoxin produced by Fusarium, a...

    ≥98%
  • C0033

    Cafestol Stearate

    Diterpene found in brewed, unfiltered coffee; F...

    ≥98%
  • C9709

    Cycloheximide

    Protein synthesis inhibitor, used to measure pr...

    ≥98%
  • A1368

    Adrenomedullin (1-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only