Name: HPGDS-inhibitor-1
SKU: H6225
Availability: InStock

Description

HPGDS Inhibitor 1 is an inhibitor of hematopoietic prostaglandin D synthase (HPGDS) that decreases release of PGD2. HPGDS Inhibitor 1 displays anti-inflammatory, anti-allergic, and immunomodulatory activities, decreasing antigen-induced immune and inflammation responses in animal models.

Product Info

Cas No.	1033836-12-2
Purity	≥98%
Formula	C₁₉H₁₉F₄N₃O
Formula Wt.	381.37
IUPAC Name	6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]nicotinamide
Synonym	Prostaglandin D Synthase (hematopoietic-type) Inhibitor I, H-PGDS Inhibitor I, MDK36122
Solubility	10 mM in DMSO

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	H6225 MSDS PDF
Info Sheet	H6225 Info Sheet PDF

References

Carron CP, Trujillo JI, Olson KL, et al. Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS). ACS Med Chem Lett. 2010 Feb 2;1(2):59-63. PMID: 24900177.

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HPGDS-inhibitor-1

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