• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Hydroxyurea

Hydroxyurea

Product ID H9715
Cas No. 127-07-1
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $87.60 In stock
10 g $165.40 In stock
50 g $486.30 In stock
100 g $680.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Hydroxyurea exhibits anticancer chemotherapeutic and antiviral activities; it inhibits ribonucleotide reductase, limiting deoxyribonucleotide production and inhibiting DNA synthesis. This compound also treats sickle cell anemia, as it increases NO levels in blood through binding of hemoglobin and stimulates production of fetal hemoglobin which is not affected by the sickle-cell gene mutation. It also treats myeloproliferative disorders and chronic myelogenous leukemia (CML)

Product Info

Cas No.

127-07-1

Purity

≥98%

Formula

CH4N2O2

Formula Wt.

76.06

IUPAC Name

hydroxyurea

Synonym

Hydroxycarbamide, Droxia, Hydrea, Litalir

Melting Point

133-136°C

Solubility

Soluble in water or hot alcohol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

H9715 MSDS PDF

Info Sheet

H9715 Info Sheet PDF

References

Amaru Calzada A, Pedrini O, Finazzi G, et al. Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients. Exp Hematol. 2013 Mar;41(3):253-60.e2. PMID: 23111067.

Vankayala SL, Hargis JC, Woodcock HL. Unlocking the binding and reaction mechanism of hydroxyurea substrates as biological nitric oxide donors. J Chem Inf Model. 2012 May 25;52(5):1288-97. PMID: 22519847.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R8179

    Rutaecarpine, synthetic

    Found in Evodia rutaecarpa; potential cAMP, 3β...

    ≥98%
  • S8248

    Sulfamethoxazole

    Sulfonamide; PABA inhibitor.

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • T1024

    Baccatin VI

    Fermentation impurity

    ≥98%
  • D183736

    19-O-Desmethoxy rapamycin

    Fermentation impurity

    ≥94%
  • A686164

    Arecaidine Hydrochloride

    mAChR agonist, selective for M2.

    ≥98%
  • A6971

    ARRY-162

    MEK1/2 and ERK inhibitor.

    ≥99%
  • D017538

    Danoprevir

    May be useful against COVID-19

    ≥98%
  • C0149

    Calcitonin, salmon

    Endogenous neuropeptide hormone, lowers extrace...

    ≥98%
  • D3208

    Diclazuril

    Coccidiostat, GAPDH inhibitor.

    ≥98%
  • V0252

    Vancomycin Hydrochloride

    Glycopeptide, binds D-Ala-D-Ala; cell wall synt...

    ≥1050 IU/mg, bio assay
  • C1627

    Cefaclor Monohydrate

    β-lactam cephalosporin; penicillin binding pro...

    ≥97%
  • C0248

    Calcineurin Substrate

    Peptide used to measure in vitro calcineurin ac...

    ≥96%
  • D3372

    Disodium Cycloheptylaminomethylene Diphosphate

    Bisphosphonate; squalene synthase inhibitor.

    ≥98%
  • A4000

    AK-1

    SIRT2 inhibitor.

    ≥99%
  • B1876

    Betamethasone

    Steroid; glucocorticoid agonist.

    ≥98%
  • G8850

    GW-5074

    c-Raf inhibitor.

    ≥98%
  • A5326

    Aniracetam

    AMPA positive allosteric modulator, D2, 5-HT2A,...

    ≥98%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • H9712

    (E)-4-Hydroxytamoxifen

    SERM.

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only