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Idoxuridine

Idoxuridine

Product ID I1257
Cas No. 54-42-2
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $94.80 In stock
1 g $173.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Idoxuridine is an antiviral clinically used to treat herpes simplex keratitis and other ocular herpes infections. Idoxuridine is a nucleoside analog of deoxyuridine that is incorporated into DNA, inhibiting chain elongation. Idoxuridine also shows benefit as a radiation/chemotherapy sensitizer in glioma cells.

Product Info

Cas No.

54-42-2

Purity

≥98%

Formula

C9H11IN2O5

Formula Wt.

354.10

Chemical Name

2'-Deoxy-5-iodouridine

IUPAC Name

1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

Synonym

IdU' IdUR, IUdR, IdUrd, Dendrid, (+)-5-Iodo-2'-deoxyuridine

Melting Point

164-166°C

Solubility

Slightly soluble in water (2 mg/mL), acetone (1.6 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

I1257 MSDS PDF

Info Sheet

I1257 Info Sheet PDF

References

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Schultz CJ, Gaffney DK, Lindstrom MJ, et al. Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance. Cancer J Sci Am. 1995 Jul-Aug;1(2):151-61. Erratum in: Cancer J Sci Am. 1996 Jan-Feb;2(1):15. PMID: 9166468.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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