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INCB-28060

INCB-28060

Product ID I5208
Cas No. 1029712-80-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $64.90 In stock
5 mg $127.20 In stock
10 mg $233.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

INCB28060 is an inhibitor of c-MET that exhibits anticancer chemotherapeutic activity. In cellular models of cancer, INCB28060 inhibits cell migration and induces apoptosis, inhibiting proliferation. In animal models, this compound inhibits tumor growth.

Product Info

Cas No.

1029712-80-8

Purity

≥98%

Formula

C23H17FN6O

Formula Wt.

412.42

IUPAC Name

2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide

Synonym

INC-280, Capmatinib

Solubility

DMSO 2 mg/mL (4.84 mM) Water Insoluble Ethanol Insoluble

Appearance

Yellow Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

I5208 MSDS PDF

Info Sheet

I5208 Info Sheet PDF

References

Liu X, Wang Q, Yang G, et al. A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3. Clin Cancer Res. 2011 Nov 15;17(22):7127-38. PMID: 21918175.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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