Description
Nitrendipine is an L-type calcium channel blocker which research has shown to have a potent inhibitory effect on human carboxylesterase, a member of the serine hydrolase family, in vitro.
Nitrendipine
Product ID N3478
Cas No. 39562-70-4
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 39562-70-4 |
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| Purity | ≥98% |
| Formula | C18H20N2O6 |
| Formula Wt. | 360.37 |
| IUPAC Name | Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate |
| Solubility | soluble 2mg/ml in ethanol, 25mg/ml in DMSO, and 30mg/ml in DMF, sparingly soluble in aqueous buffers |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Ohno S, Yokoi H, Mori K, et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep. 2016 Jun 7; 6:27192. PMID: 27273361.
Yanjiao X, Chengliang Z, Xiping L, et al. Evaluation of the inhibitory effects of antihypertensive drugs on human carboxylesterase in vitro. Dru Metab Pharmacokinet. 2013; 28(6):468-474. PMID: 23648675.