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Nitrendipine

Product ID N3478
Cas No. 39562-70-4
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $59.20 In stock
100 mg $183.80 In stock
500 mg $413.50 In stock
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  • Description
  • Product Info
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  • Description
  • Product Info
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  • References
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Description

Nitrendipine is an L-type calcium channel blocker which research has shown to have a potent inhibitory effect on human carboxylesterase, a member of the serine hydrolase family, in vitro.

Product Info

Cas No.

39562-70-4

Purity

≥98%

Formula

C18H20N2O6

Formula Wt.

360.37

Chemical Name

5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

IUPAC Name

Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate

Synonym

Baypress, Bayotensin, Nidrel

Solubility

soluble 2mg/ml in ethanol, 25mg/ml in DMSO, and 30mg/ml in DMF, sparingly soluble in aqueous buffers

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N3478 MSDS PDF

Info Sheet

N3478 Info Sheet PDF

References

Ohno S, Yokoi H, Mori K, et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep. 2016 Jun 7; 6:27192. PMID: 27273361.

Yanjiao X, Chengliang Z, Xiping L, et al. Evaluation of the inhibitory effects of antihypertensive drugs on human carboxylesterase in vitro. Dru Metab Pharmacokinet. 2013; 28(6):468-474. PMID: 23648675.

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