Description
Nitrendipine is an L-type calcium channel blocker which research has shown to have a potent inhibitory effect on human carboxylesterase, a member of the serine hydrolase family, in vitro.
Product Unit Size | Cost | Quantity | Stock |
---|
Nitrendipine is an L-type calcium channel blocker which research has shown to have a potent inhibitory effect on human carboxylesterase, a member of the serine hydrolase family, in vitro.
Cas No. | 39562-70-4 |
---|---|
Purity | ≥98% |
Formula | C18H20N2O6 |
Formula Wt. | 360.37 |
Chemical Name | 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
IUPAC Name | Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate |
Synonym | Baypress, Bayotensin, Nidrel |
Solubility | soluble 2mg/ml in ethanol, 25mg/ml in DMSO, and 30mg/ml in DMF, sparingly soluble in aqueous buffers |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Ohno S, Yokoi H, Mori K, et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep. 2016 Jun 7; 6:27192. PMID: 27273361.
Yanjiao X, Chengliang Z, Xiping L, et al. Evaluation of the inhibitory effects of antihypertensive drugs on human carboxylesterase in vitro. Dru Metab Pharmacokinet. 2013; 28(6):468-474. PMID: 23648675.
DAT inhibitor.
Iron chelator.
β-lactam cephalosporin; penicillin binding pro...
Thiazolidinedione; PPARγ agonist.
Snake venom found in Bothrops neuwiedi diporus;...
Tetracycline; protein translation inhibitor, po...
α1-adrenergic antagonist.
GnRH analog; GnRH1 agonist.
Corticosteroid
Dihydrofolate reductase inhibitor.
NSAID; GABA-A potentiator, COX-1/2 inhibitor.
Insect sterilizer; mutagenic.
Synthetic fluorinated thiamphenicol analog; pro...
Semi-synthetic diterpene originally found in Ta...
BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, vol...
Endogenous precursor to all steroid hormones; T...
FK506 analog; calcineurin inhibitor.
Alkaloid found in Sophora.
STING inhibitor
COMT inhibitor.