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Itopride Hydrochloride

Itopride Hydrochloride

Product ID I7757
Cas No. 122892-31-3
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $97.70 In stock
1 g $147.20 In stock
5 g $525.90 In stock
25 g $1,126.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Itopride is an inhibitor of acetylcholinesterase (AChE) and D2 receptors; it exhibits prokinetic gastrointestinal motility modulating activity. Itopride is clinically used to treat functional dyspepsia and gastroesophageal reflux disease (GERD). Itopride inhibits lower esophageal sphincter relaxation.

Product Info

Cas No.

122892-31-3

Purity

≥98%

Formula

C20H26N2O4 HCl

Formula Wt.

394.88

Chemical Name

N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4- dimethoxy-benzamide

IUPAC Name

N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3, 4-dimethoxybenzamide;hydrochloride

Melting Point

191-195°C

Solubility

Soluble in water or methanol. Sparingly soluble in acetic acid.

Appearance

White to off-white crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I7757 MSDS PDF

Info Sheet

I7757 Info Sheet PDF

References

Huang X, Lv B, Zhang S, et al. Itopride therapy for functional dyspepsia: a meta-analysis. World J Gastroenterol. 2012 Dec 28;18(48):7371-7. PMID: 23326147.

Scarpellini E, Vos R, Blondeau K, et al. The effects of itopride on oesophageal motility and lower oesophageal sphincter function in man. Aliment Pharmacol Ther. 2011 Jan;33(1):99-105. PMID: 21083582.

Lim HC, Kim YG, Lim JH, et al. Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. PMID: 18581598.

Fujitsuka N, Asakawa A, Hayashi M, et al. Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry. 2009 May 1;65(9):748-759. PMID: 19058784.

Custom Order

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