• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Kaempferol

Kaempferol

Product ID K0117
Cas No. 520-18-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $50.90 In stock
5 mg $71.50 In stock
10 mg $81.70 In stock
25 mg $142.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Kaempferol is a flavonol found in many plant sources that exhibits antioxidative, anti-inflammatory, neuroprotective, anti-angiogenic, anti-metastatic, anti-obesity, and anticancer chemotherapeutic activities. Kaempferol inhibits LPS-induced release of TNF-α, IL-1β, IL-6, and IL-18 as well as activation of NF-κB and Akt in vitro. In neurons, kaempferol decreases glutamate-induced increases in ROS levels and oxidative stress. In animal models of bladder cancer, this compound inhibits cell proliferation, induces apoptosis, and decreases tumor growth. In vitro, kaempferol also decreases adipogenesis, suppresses triglyceride synthesis, and increases lipolysis. Kaempferol inhibits VEGF secretion and angiogenesis in cellular models. In osteosarcoma cells, this compound inhibits cell migration by decreasing expression of uPA and matrix metalloproteinases 2 and 9 (MMP2/9).

Product Info

Cas No.

520-18-3

Purity

≥98%

Formula

C15H10O6

Formula Wt.

286.24

Chemical Name

3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzo- pyran-4-one

IUPAC Name

3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one

Synonym

Nimbecetin, Populnetin, Rhamnolutein, Robigenin, Swartziol, Trifolitin

Melting Point

276-278°C

Solubility

Slightly soluble in water. Soluble in hot alcohol, ether or alkalies.

Appearance

Yellow Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

K0117 MSDS PDF

Info Sheet

K0117 Info Sheet PDF

References

Tang XL, Liu JX, Dong W, et al. Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. Inflammation. 2014 Sep 5. [Epub ahead of print]. PMID: 25189464.

Yang EJ, Kim GS, Jun M, et al. Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells. Food Funct. 2014 Jul 25;5(7):1395-402. PMID: 24770605.

Dang Q, Song W, Xu D, et al. Kaempferol suppresses bladder cancer tumor growth by inhibiting cell proliferation and inducing apoptosis. Mol Carcinog. 2014 Apr 2. [Epub ahead of print]. PMID: 24700700.

Chen HJ, Lin CM, Lee CY, et al. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncol Rep. 2013 Aug;30(2):925-32. PMID: 23708932.

Park UH, Jeong JC, Jang JS, et al. Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells. Biol Pharm Bull. 2012;35(9):1525-33. PMID: 22975504.

Luo H, Rankin GO, Juliano N, et al. Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Food Chem. 2012 Jan 15;130(2):321-328. PMID: 21927533.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%
  • F5872

    N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • B5000

    BMS-911543

    JAK2 inhibitor.

    ≥99%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • D0263

    Dapoxetine Hydrochloride

    SERT inhibitor, potential voltage-gated K+ chan...

    ≥99%
  • C1629

    Cefoperazone Acid

    β-lactam cephalosporin; penicillin binding pro...

    ≥98%
  • M5675

    Motilin, canine

    Endogenous peptide hormone; motilin agonist.

    ≥95%
  • D0010

    3H-1,2-Dithiole-3-thione

    Induces activation of Nrf2; inhibits apoptosis ...

    ≥98%
  • A0248

    BAM-12P

    Peptide, cleavage product of proenkephalin; κO...

    ≥95%
  • T7033

    Trifluoperazine Dihydrochloride

    Phenothiazine; D1/2 and α1-adrenergic antagoni...

    ≥98%
  • O4104

    Okadaic Acid Sodium

    Shellfish toxin produced by dinoflagellates and...

    ≥98%
  • B165121

    Bedaquiline Fumarate

    Bactericidal

    ≥98%
  • P7318

    Pseudoginsenoside F11

    Saponin found in species of Panax; PPARγ agoni...

    ≥98%
  • Z160021

    Zearalanone

    Mycotoxin.

    ≥97%
  • I1418

    Idebenone

    Synthetic quinone CoQ analog, promotes mitochon...

    ≥98%
  • T6934

    Trimebutine Maleate

    L-type Ca2+ channel blocker, BK K+ channel modu...

    ≥96%
  • B3278

    Biotin

    Water-soluble coenzyme, vitamin (B7) found in v...

    ≥98%
  • K0022

    K252b

    Staurosporine analog; PKC inhibitor.

    ≥98%
  • F3473

    Fisetin

    Flavonoid found in various plant sources; matri...

    ≥97%
  • N3310

    Nicotinamide

    Amide form of vitamin B3 required for productio...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only