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Kinetensin is a rapidly metabolized analog of neurotensin. Kinetensin induces histamine release in peritoneal mast cells, increasing vascular permeability in vivo. Unlike neurotensin, kinetensin does not exhibit modulation of muscle contractility.
| Cas No. | 103131-69-7 |
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| Purity | ≥95% |
| Formula | C56H85N17O11 |
| Formula Wt. | 1172.4 |
| IUPAC Name | (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid |
| Synonym | Neurotensin-related peptide |
| Solubility | Soluble in water (2 mg/mL). |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Read D, Shulkes A, Fletcher D, et al. Pharmacokinetics and biological activity of kinetensin in conscious sheep. Agents Actions. 1993 Mar;38(3-4):231-9. PMID: 8213349.
Sydbom A, Ware J, Mogard MH. Stimulation of histamine release by the peptide kinetensin. Agents Actions. 1989 Apr;27(1-2):68-71. PMID: 2473637.