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L-Carnitine Hydrochloride

L-Carnitine Hydrochloride

Product ID C0263
Cas No. 6645-46-1
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $31.10 In stock
5 g $52.90 In stock
25 g $159.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
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  • Custom Order

Description

L-Carnitine is an endogenous quaternary ammonium compound required for fatty acid transport; it is often given as a dietary supplement. The L-isomer is active, exhibiting anti-osteoporotic, antioxidative, and cardioprotective activities. In a clinical setting, L-carnitine administration increases muscle carnitine content and work output while decreasing glycogen utilization during exercise. Additionally, L-carnitine improves postprandial flow-mediated dilation, slightly increasing vascular function. In animal models, L-carnitine increases bone mineral density and decreases bone resorption. L-Carnitine also improves plasma markers of exercise stress such as malondialdehyde. L-Carnitine improves symptoms of cardiovascular disease accompanying myocardial infarction and decreases ventricular arrhythmias, symptoms of angina, and mortality rates.

Product Info

Cas No.

6645-46-1

Purity

≥98%

Formula

C7H15NO3 HCl

Formula Wt.

197.66

Chemical Name

3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-prop- anaminium inner salt hydrochloride

IUPAC Name

(3-carboxy-2-hydroxypropyl)-trimethylazanium;chloride

Synonym

Lefcar, Metina

Melting Point

142°C (dec.)

Solubility

Water, Ethanol (25 mg/mL)

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C0263 MSDS PDF

Info Sheet

C0263 Info Sheet PDF

References

DiNicolantonio JJ, Lavie CJ, Fares H, et al. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013 Jun;88(6):544-51. PMID: 23597877.

Wall BT, Stephens FB, Constantin-Teodosiu D, et al. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans. J Physiol. 2011 Feb 15;589(Pt 4):963-73. PMID: 21224234.

Volek JS, Judelson DA, Silvestre R, et al. Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. Am J Cardiol. 2008 Nov 15;102(10):1413-7. PMID: 18993165.

Hooshmand S, Balakrishnan A, Clark RM, et al. Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats. Phytomedicine. 2008 Aug;15(8):595-601. PMID: 18539446.

Volek JS, Kraemer WJ, Rubin MR, et al. L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E474-82. PMID: 11788381.

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