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L-(-)-Norepinephrine Bitartrate Monohydrate

L-(-)-Norepinephrine Bitartrate Monohydrate

Product ID N5766
Cas No. 108341-18-0
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $142.90 In stock
1 g $245.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Norepinephrine is a hormone and neurotransmitter that modulates sympathetic nervous system activity and plays a role in modulating reward, reinforcement, feeding, and other behaviors. Norepinephrine exhibits vasoconstrictive, pro-angiogenic, and thermoregulatory activities. Norepinephrine is clinically used to treat cardiac arrest, severe hypotension, and shock. This compound acts as an agonist at α- and β-adrenergic receptors, inducing vascular vasoconstriction, decreasing blood flow, and increasing blood pressure. In vitro, norepinephrine increases expression of VEGF and stimulates choroidal neovascularization. This compound also decreases code body temperature.

Product Info

Cas No.

108341-18-0

Purity

≥98%

Formula

C8H11NO3 • C4H6O6 • H2O

Formula Wt.

337.28

Chemical Name

4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol d-Bitartrate

IUPAC Name

4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;(2R,3R)-2, 3-dihydroxybutanedioic acid;hydrate

Synonym

Norepinephrine d-Bitartrate, Levarterenol bitartrate, L-Noradrenaline

Melting Point

102-104°C

Solubility

Soluble in water (400 mg/mL). Slightly soluble in ethanol (3 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N5766 MSDS PDF

Info Sheet

N5766 Info Sheet PDF

References

Lavine JA, Sang Y, Wang S, et al. Attenuation of choroidal neovascularization by β(2)-adrenoreceptor antagonism. JAMA Ophthalmol. 2013 Mar;131(3):376-82. PMID: 23303344.

Liang MJ, He LC, Yang GD. Screening, analysis and in vitro vasodilatation of effective components from Ligusticum Chuanxiong. Life Sci. 2005 Nov 26;78(2):128-33. PMID: 16154159.

Weiser M, Hilz MJ, Bronfin L, et al. Assessing microcirculation in familial dysautonomia by laser Doppler flowmeter. Clin Auton Res. 1998 Feb;8(1):13-23. PMID: 9532416.

Laudenslager ML. The influence of hypothalamic temperature on some thermoregulatory effects of hypothalamic injections of norepinephrine. Pharmacol Biochem Behav. 1976 Dec;5(6):713-6. PMID: 828727.

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