• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Linezolid

Linezolid

Product ID L3453
Cas No. 165800-03-3
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $61.40 In stock
1 g $163.00 In stock
5 g $419.50 In stock
25 g $958.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Linezolid is an oxazolidinone antibiotic that exhibits antibacterial activity against gram positive bacteria. Linezolid binds to the A site of 23S rRNA on the 50S ribosomal subunit, inhibiting protein synthesis. Linezolid also decreases NMDA receptor-mediated current, but is less active than most other comparable antibacterial compounds.

Product Info

Cas No.

165800-03-3

Purity

≥99%

Formula

C16H20FN3O4

Formula Wt.

337.35

Chemical Name

(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

IUPAC Name

N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Synonym

Zyvox, Zyvoxid

Melting Point

178-182C

Solubility

Moderately soluble in water (3 mg/mL). Soluble in DMSO (>20 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L3453 MSDS PDF

Info Sheet

L3453 Info Sheet PDF

References

Long KS, Vester B. Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother. 2012 Feb;56(2):603-12. PMID: 22143525.

Kombian SB, Phillips OA. In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons. Neuroscience. 2011 Apr 28;180:53-63. PMID: 21296129.

Ippolito JA, Kanyo ZF, Wang D, et al. Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. J Med Chem. 2008 Jun 26;51(12):3353-6. PMID: 18494460.

Brickner SJ, Hutchinson DK, Barbachyn MR, et.al. Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections. J Med Chem. 1996 Feb 2;39(3):673-9. PMID: 8576909 DOI: 10.1021/jm9509556

Goetz J, Keyssner V, Hanses F, et al. Animal experimental investigation on the efficacy of antibiotic therapy with linezolid, vancomycin, cotrimoxazole, and rifampin in treatment of periprosthetic knee joint infections by MSRA. Bone Joint Res. 2022 Mar;11(3):143-151. PMID: 35227086.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D1694

    Dexamethasone Acetate Monohydrate

    Steroid; glucocorticoid agonist.

    ≥98%
  • A7210

    L-(+)-Ascorbic Acid

    Form of vitamin C found in various plant and fo...

    ≥98%
  • G0278

    Gatifloxacin Sesquihydrate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • B011458

    Baloxavir

    Cap-dependent endonuclease inhibitor

    ≥ 99%
  • T3202

    Tianeptine

    μOR and δOR agonist, D2/D3 DA potentiator.

    ≥98%
  • M174446

    Meleagrin

    FabI inhibitor

    ≥99%
  • P6956

    Prostaglandin E1

    Endogenous prostaglandin, vasodilator.

    ≥98%
  • S3033

    Shikimic Acid

    Cyclohexanecarboxylic acid found in various pla...

    ≥98%
  • S1872

    Sesamin

    Lignin found in Sesamin indicum;

    ≥98%
  • M576486

    Mometasone Furoate

    Synthetic glucocorticoid

    ≥98%
  • A484091

    Amcinonide

    Glucocorticoid

    ≥98%
  • A5225

    α-ANP (1-28), human

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥95%
  • N8561

    NVP-AEW541

    IGF-1R inhibitor.

    ≥98%
  • P2502

    Phenethyl Glucosinolate Potassium

    Found in cruciferous vegetables.

    ≥97%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • P3269

    Piroxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • N5769

    Norfloxacin Nicotinate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • C2802

    CH5132799

    p110α PI3K inhibitor.

    ≥98%
  • C2900

    CH5424802

    ALK inhibitor.

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only