Description
Loxapine is an inhibitor of dopamine receptors D2 and D4. It is a serotonin receptor antagonist and displays antipsychotic properties. It is used to treat acute agitation in patients with bipolar disorder or schizophrenia.
Loxapine Succinate
Product ID L589921
Cas No. 27833-64-3
Purity ≥99%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 27833-64-3 |
|---|---|
| Purity | ≥99% |
| Formula | C18H18ClN3O • C4H6O4 |
| Formula Wt. | 445.90 |
| Chemical Name | 2-chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]oxazepine succinate |
| IUPAC Name | butanedioic acid;8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
| Synonym | Loxapine succinate salt, Cloxazepine, Daxolin, Loxapac |
| Solubility | Insoluble in water. Ethanol 2 mg/mL DMSO 80 mg/mL |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
de Berardis D., Fornaro M., et al. The Role of Inhaled Loxapine in the Treatment of Acute Agitation in Patients with Psychiatric Disorders: A Clinical Review. Int J Mol Sci. 18(2) (2017). PMID: 28208695.
Pollack C. Inhaled loxapine for the urgent treatment of acute agitation associated with schizophrenia or bipolar disorder. Curr Med Res Opin. 32(7):1253-60 (2016). PMID: 27121764.