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LY-3200882

LY-3200882

Product ID L960010
Cas No. 1898283-02-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $136.30 In stock
25 mg $340.70 In stock
100 mg $885.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

LY-3200882 is an inhibitor of TGFβR1. The TGF-β pathway is frequently deregulated in tumors, and plays an important role in the regulation of cell growth, differentiation, and apopsosis. Preliminary safety and efficacy studies suggest that LY-3200882 is for patients with certain advanced or metastatic cancers, for example it inhibits tumor growth in preclinical models of triple negative breast cancer.

Product Info

Cas No.

1898283-02-7

Purity

≥98%

Formula

C24H29N5O3

Formula Wt.

435.53

Chemical Name

LY-3200882

IUPAC Name

2-{4-[(4-{[1-Cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy}-2-pyridinyl)amino]-2-pyridinyl}-2-propanol

Synonym

LY 3200882, LY3200882

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

L960010 MSDS PDF

Info Sheet

L960010 Info Sheet PDF

References

Huaxing P., Saravanan P., et al. LY3200882, a novel, highly selective TGFβRI small molecule inhibitor. Cancer Research. 77(13 Suppl): Abstract nr 955.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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