LKT Labs

Biochemicals for Life Science Research

Methyl Salicylate

Methyl Salicylate

Product ID M1979
Cas No. 119-36-8
Purity ≥98%
Product Unit SizeCostQuantityStock
250 ml $50.00 In stock
500 mL $86.00 In stock
1 L $140.00 In stock
Bulk Quote

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Description

Methyl salicylate can be found in Spiraea, Betula, and Gaultheria; it exhibits analgesic activity. Methyl salicylate is commercially used as an antiseptic, a wintergreen flavorant/tastant, and as a fragrance. In vitro, methyl salicylate displays both agonist and antagonist activity at transient receptor potential vanilloid 1 (TRPV1) channels. Metabolites of methyl salicylate exhibit anti-inflammatory and analgesic activities in vivo similar to those displayed by most non-steroidal anti-inflammatory drugs (NSAIDs).

Product Info

Cas No.

119-36-8
Purity

≥98%
Formula

C8H8O3
Formula Wt.

152.15
Chemical Name

2-Hydroxybenzoic acid methyl ester
IUPAC Name

methyl 2-hydroxybenzoate
Synonym

Wintergreen Oil, Betula Oil, Sweet Birch Oil
Melting Point

-8.6°C

Solubility

Sparingly soluble in water. Soluble in chloroform and ether.

Appearance

Clear, Colorless Liquid

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

M1979 MSDS PDF
Info Sheet

M1979 Info Sheet PDF
Brochures

TRP Channel Modulator Flyer

References

Tieman D, Zeigler M, Schmelz E, et al. Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate. Plant J. 2010 Apr 1;62(1):113-23. PMID: 20070566.

Ohta T, Imagawa T, Ito S. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Mol Pharmacol. 2009 Feb;75(2):307-17. PMID: 18987162.

James DG, Price TS. Field-testing of methyl salicylate for recruitment and retention of beneficial insects in grapes and hops. J Chem Ecol. 2004 Aug;30(8):1613-28. PMID: 15537163.

Mason L, Moore RA, Edwards JE, et al. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain. BMJ. 2004 Apr 24;328(7446):995. PMID: 15033879.

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