Methyl Salicylate

Name: Methyl Salicylate
SKU: M1979
Availability: InStock

Product ID M1979

Cas No. 119-36-8

Purity ≥98%

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Description

Methyl salicylate can be found in Spiraea, Betula, and Gaultheria; it exhibits analgesic activity. Methyl salicylate is commercially used as an antiseptic, a wintergreen flavorant/tastant, and as a fragrance. In vitro, methyl salicylate displays both agonist and antagonist activity at transient receptor potential vanilloid 1 (TRPV1) channels. Metabolites of methyl salicylate exhibit anti-inflammatory and analgesic activities in vivo similar to those displayed by most non-steroidal anti-inflammatory drugs (NSAIDs).

Product Info

Cas No.	119-36-8
Purity	≥98%
Formula	C₈H₈O₃
Formula Wt.	152.15
Chemical Name	2-Hydroxybenzoic acid methyl ester
IUPAC Name	methyl 2-hydroxybenzoate
Synonym	Wintergreen Oil, Betula Oil, Sweet Birch Oil
Melting Point	-8.6°C
Solubility	Sparingly soluble in water. Soluble in chloroform and ether.
Appearance	Clear, Colorless Liquid

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	M1979 MSDS PDF
Info Sheet	M1979 Info Sheet PDF
Brochures	TRP Channel Modulator Flyer

References

Tieman D, Zeigler M, Schmelz E, et al. Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate. Plant J. 2010 Apr 1;62(1):113-23. PMID: 20070566.

Ohta T, Imagawa T, Ito S. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methylsalicylate. Mol Pharmacol. 2009 Feb;75(2):307-17. PMID: 18987162.

James DG, Price TS. Field-testing of methyl salicylate for recruitment and retention of beneficial insects in grapes and hops. J Chem Ecol. 2004 Aug;30(8):1613-28. PMID: 15537163.

Mason L, Moore RA, Edwards JE, et al. Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain. BMJ. 2004 Apr 24;328(7446):995. PMID: 15033879.

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Methyl Salicylate

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

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