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Micafungin, an echinocandin, exhibits fungicidal and fungistatic activities through the inhibition of 1,3-beta-D-glucan synthesis. It was also found to have antiviral effects against various viruses including the coronavirus SARS-CoV-2 and its variants.
| Cas No. | 235114-32-6 |
|---|---|
| Purity | ≥95% |
| Formula | C56H71N9O23S |
| Formula Wt. | 1270.28 |
| IUPAC Name | [5-[(1S,2S)-2-[(3S,6S,9S,11R,15S,18S,20R,21R,24S,25S,26S)-3-[(1R)-3-amino-1-hydroxy-3-oxopropyl]-11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-[[4-[5-(4-pentoxyphenyl)-1,2-oxazol-3-yl]benzoyl]amino]-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl] hydrogen sulfate |
| Synonym | Funguard; Mycamine; FK 463 |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
J J Vehreschild and O A Cornely, Micafungin sodium, the second of the echinocandin class of antifungals: theory and practice. Future Microbiol. 2006, 1:161-70.
D Cappelletty and K Eiselstein-McKitrick, The echinocandins. Pharmacotherapy 2007, 27:369-88.
S Nakajima, H Ohashi, D. Akazawa, et al. Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication. Viruses. 2023 15:452.