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Myelin Basic Protein (1-11), human

Myelin Basic Protein (1-11), human

Product ID M9643
Cas No. 106128-98-7
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $65.10 In stock
2 mg $108.00 In stock
5 mg $193.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Myelin basic protein (1-11) is a peptide antigen fragment that may bind to receptors expressed by T cells involved in autoimmune diseases such as multiple sclerosis. Administration of myelin basic protein (1-11) decreases expression of IL-12 in the lymph nodes of mice with experimental autoimmune encephalitis (EAE), an animal model of multiple sclerosis; IL-12 appears to play a protective role against EAE pathology and development.

Product Info

Cas No.

106128-98-7

Purity

≥95%

Formula

C52H88N22O17

Formula Wt.

1293.42

IUPAC Name

N-Acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-N5-(diaminomethylen)-L-ornithyl-L-prolyl-L-seryl-L-glutaminyl-N5-(diaminomethylen)-L-ornithyl-L-histidylglycin

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M9643 MSDS PDF

Info Sheet

M9643 Info Sheet PDF

References

Buenafe AC, Sherwood C, Moes N, et al. Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice. J Neurosci Res. 2009 Jan;87(1):42-9. PMID: 18752298.

Zhang GX, Xu H, Kishi M, et al. The role of IL-12 in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis. J Immunol. 2002 Mar 1;168(5):2501-7. PMID: 11859144.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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