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Netilmicin Sulfate

Netilmicin Sulfate

Product ID N1976
Cas No. 56391-57-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $118.40 In stock
5 mg $347.10 In stock
10 mg $520.60 In stock
25 mg $1,041.50 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Netilmicin is an aminoglycoside antibiotic that displays activity against both gram positive and gram negative bacteria, although it is most effective against gram negative bacteria. Netilmicin binds 16s rRNA of the bacterial 30S ribosome, inhibiting translation and tRNA translocation. Netilmicin also decreases melanocyte viability, tyrosinase activity, and melanin production in vitro.

Product Info

Cas No.

56391-57-2

Purity

≥98%

Formula

(C21H41N5O7)2 • 5H2SO4

Formula Wt.

1441.56

Chemical Name

O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabino- pyranosyl-(1->6)-O-[2,6-diamino-2,3,4,6-tetradeoxy- α-D-glycero-hex-4-enopyranosyl-(1->4)]-2-deoxy-N1- ethyl-D-streptamine sulfate

IUPAC Name

(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[(2S, 3R)-3-amino-6-(aminomethyl)-3, 4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5- methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid

Synonym

Certomycin, Netilyn, Netromycin, Nettacin, Zetamicin

Solubility

Soluble in water.

Appearance

White to Yellowish-white Crystalline Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

N1976 MSDS PDF

Info Sheet

N1976 Info Sheet PDF

References

Wrześniok D, Beberok A, Otreba M, et al. Netilmicin-induced modulation of melanogenesis in HEMa-LP melanocytes. Acta Pol Pharm. 2013 Sep-Oct;70(5):803-8. PMID: 24147358.

Liu TX, Xue XD, Wei LH, et al. Study of plasmid-mediated 16S rRNA methylase genes and drug-resistant transferability of Acinetobacter baumannii isolated from burn ward. Zhonghua Shao Shang Za Zhi. 2009 Apr;25(2):98-102. PMID: 19799032.

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