• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Nifekalant Hydrochloride

Nifekalant Hydrochloride

Product ID N3422
Cas No. 130656-51-8
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $97.70 In stock
10 mg $157.80 In stock
25 mg $330.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nifekalant is an antagonist at potassium channels that is clinically used to treat ventricular tachyarrhythmia; it is a class III anti-arrhythmic that increases the time course of myocardial repolarization and may prolong the QT interval. Nifekalant may also be used to treat atrial fibrillation, as it increases right atrial monophasic action potential duration and the atrial effective refractory period in subjects with atrial fibrillation.

Product Info

Cas No.

130656-51-8

Purity

≥98%

Formula

C19H27N5O5 • HCl

Formula Wt.

441.91

Chemical Name

6-[2-[(N-2-Hydroxyethyl)-3-(4-nitrophenyl)-propyl- amino(ethylamino)-1,3-dimethyl-1H,3H - pyrimidine- 2,4-dione monohydrochloride

IUPAC Name

6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1, 3-dimethylpyrimidine-2,4-dione;hydrochloride

Synonym

MS 551

Appearance

Cream-colored crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N3422 MSDS PDF

Info Sheet

N3422 Info Sheet PDF

References

Harayama N, Nihei SI, Nagata K, et al. Comparison of nifekalant and amiodarone for resuscitation of out-of-hospital cardiopulmonary arrest resulting from shock-resistant ventricular fibrillation. J Anesth. 2014 Jan 5. [Epub ahead of print]. PMID: 24389941.

Sonoda K, Watanabe I, Ohkubo K, et al. Rate-dependent electrophysiologic effects of the class III antiarrhythmic drugs nifekalant, amiodarone, and ibutilide on the atrium in patients with persistent atrial fibrillation. Int Heart J. 2013;54(5):279-84. PMID: 24097216.

Pantazopoulos IN, Troupis GT, Pantazopoulos CN, et al. Nifekalant in the treatment of life-threatening ventricular tachyarrhythmias. World J Cardiol. 2011 Jun 26;3(6):169-76. PMID: 21772943.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S7601

    Statil

    Aldose reductase inhibitor.

    ≥98%
  • M7530

    [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

    Semi-synthetic peptide, melanocortin analog; MC...

    ≥98%
  • T1025

    D-Seco Paclitaxel

    D-Seco Paclitaxel is an impurity in the product...

    ≥90%
  • A6818

    Arenobufagin

    Bufanolide steroid found in Bufo arenarum;VEGFR...

    ≥98%
  • F334453

    Filipin III

    Antifungal antibiotic

    ≥95%
  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • A1218

    Adefovir Dipivoxil

    Acyclic nucleotide (adenosine) analog, adefovir...

    ≥98%
  • T1004

    Paclitaxel Oxetane Ring-Opened 3-Acetyl 4-Benzoyl Impurity

    Synthesis impurity

    ≥92%
  • V0352

    Vandetanib

    RET, EGFR, VEGFR2 inhibitor.

    ≥98%
  • S8247

    Sulfasalazine

    Mesalazine derivative, sulfa drug; sepiapterin ...

    ≥98%
  • C0255

    Cantharidin

    Toxin produced by Canarthis vesicatoria; PP1/2A...

    ≥98%
  • T2668

    TGR5 Receptor Agonist

    TGR5 agonist.

    ≥99%
  • H1992

    Hexaconazole

    Triazole; demethylation inhibitor.

    ≥95%
  • D017538

    Danoprevir

    May be useful against COVID-19

    ≥98%
  • A6823

    Argatroban

    Thrombin inhibitor.

    ≥98%
  • A0968

    Adrenocorticotropic Hormone (1-24), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • T1844

    Telbivudine

    Nucleoside (thymidine) analog; DNA chain termin...

    ≥98%
  • D5746

    Dolasetron

    5-HT3 antagonist.

    ≥98%
  • G3358

    Ginkgolide ABC

    Mixture of Ginkgolides A, B and C, found in Gin...

    ≥98%
  • M964098

    Mycophenolate Mofetil

    Prodrug of the compound mycophenolic acid.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only