• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

Product ID M7530
Cas No. 75921-69-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $52.50 In stock
2.5 mg $105.00 In stock
5 mg $210.00 In stock
25 mg $840.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Melanotan-I (NDP-MSH) is a semi-synthetic melanocortin analog that activates the melanocortin receptor. NDP-MSH exhibits both pro-inflammatory and anti-inflammatory activities in various models. In animal models of liver regeneration, NDP-MSH increases levels of IL-6, promotes signaling by STAT and SOCS, and inhibits the decline in IκBα levels. In animal models of peritonitis, NDP-MSH decreases neutrophil trafficking and inhibits vascular leakage and leukocyte rolling and adhesion. Additionally, NDP-MSH inhibits subarachnoid hemorrhage-induced stress, inflammation, vascular remodeling, and apoptosis in other animal models.

Product Info

Cas No.

75921-69-6

Purity

≥98%

Formula

C78H111N21O19

Formula Wt.

1646.9

Synonym

NDP-MSH, Melanotan I, afamelanotide

Solubility

Soluble in water (0.6 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M7530 MSDS PDF

Info Sheet

M7530 Info Sheet PDF

References

Lonati C, Carlin A, Leonardi P, et al. Modulatory effects of NDP-MSH in the regenerating liver after partial hepatectomy in rats. Peptides. 2013 Dec;50:145-52. PMID: 24446557.

Figueiredo J, Ferreira AE, Silva RL, et al. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn Schmiedebergs Arch Pharmacol. 2013 Apr;386(4):311-8. PMID: 23338711.

Gatti S, Lonati C, Acerbi F, et al. Protective action of NDP-MSH in experimental subarachnoid hemorrhage. Exp Neurol. 2012 Mar;234(1):230-8. PMID: 22230666.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P3563

    Piperlonguminine

    Found in Piper longum.

    ≥99%
  • R3013

    Recombinant TpN 44.50 protein

    Recombinant protein containing Treponema pallid...

    ≥95%
  • T1030

    N-Des-2-methylpropan-2-ol Docetaxel

    N-Des-2-methylpropan-2-ol Docetaxel is an impur...

    ≥90%
  • N1744

    Nelarabine

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • E9317

    Exemestane

    Aromatase inhibitor.

    ≥97%
  • T1853

    Tenovin-6

    SIRT1/2 inhibitor, indirect p53 activator.

    ≥98%
  • R8206

    Rubescensin A

    Diterpene originally found in Rabdosia.

    ≥93%
  • A5070

    Angiotensin Acetate

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • T3584

    Tivantinib

    MET and GSK-3α/β inhibitor.

    ≥98%
  • S7618

    StemRegenin 1 Hydrochloride

    AhR antagonist.

    ≥98%
  • A4805

    Amastatin Hydrochloride Hydrate

    Aminopeptidase inhibitor.

    ≥98%
  • R1780

    trans-Retinoic Acid

    Vitamin A carboxylic acid; RAR agonist.

    ≥98%
  • S9755

    (R)-Synephrine

    Synephrine is an endogenous alkaloid.

    ≥98%
  • P1969

    Perifosine

    Alkylphospholipid analog; Akt inhibitor.

    ≥98%
  • K0117

    Kaempferol

    Flavonol found in various plant sources.

    ≥98%
  • I7258

    Isoflurane

    Ca2+ ATPase and ATP-sensitive K+ channel activa...

    ≥98%
  • F1652

    Fenbufen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • V0147

    Valproic Acid Sodium

    T-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • Y4802

    YM-201636

    PIKfyve inhibitor.

    ≥98%
  • A9710

    AZD-2014

    mTOR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only