• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Oxcarbazepine

Oxcarbazepine

Product ID O9210
Cas No. 28721-07-5
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $104.10 In stock
5 g $330.00 In stock
25 g $1,080.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Oxcarbazepine (OX) is an antiepileptic/anticonvulsant commonly used to treat epilepsy, but also exhibits activity as a treatment for mood disorders and neuropathic pain as well. Administration of oxcarbazepine leads to a reversible reduction in current amplitude from voltage-gated Na+ channels and may suppress current amplitude of delayed rectifying K+ channels; this reduces the amplitude of action potentials and prolongs their duration. This compound also inhibits Na+ channel-dependent Glu release and produces a moderate open channel block on nicotinic acetylcholine receptors (nAChRs), preventing deactivation. Interestingly, oxcarbazepine may have potential as a treatment for substance abuse disorders, as it is moderately effective as a relapse prevention treatment in a clinical trial of recently abstinent alcohol-dependent subjects.

Product Info

Cas No.

28721-07-5

Purity

≥98%

Formula

C15H12N2O2

Formula Wt.

252.27

Chemical Name

10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5- carboxamide

IUPAC Name

5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide

Synonym

Trileptal

Melting Point

215-216°C

Solubility

Soluble in DMSO (9mg/mL).

Appearance

White or Almost White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

O9210 MSDS PDF

Info Sheet

O9210 Info Sheet PDF

References

Di Resta C, Ambrosi P, Curia G, et al. Effect of carbamazepine and oxcarbazepine on wild-type and mutant neuronal nicotinic acetylcholine receptors linked to nocturnal frontal lobe epilepsy. Eur J Pharmacol. 2010 Sep 15;643(1):13-20. PMID: 20561518.

Johannessen Landmark C, Johannessen SI. Pharmacological management of epilepsy: recent advances and future prospects. Drugs. 2008;68(14):1925-39. PMID: 18778117.

Huang CW, Huang CC, Lin MW, et al. The synergistic inhibitory actions of oxcarbazepine on voltage-gated sodium and potassium currents in differentiated NG108-15 neuronal cells and model neurons. Int J Neuropsychopharmacol. 2008 Aug;11(5):597-610. PMID: 18184444.

Sitges M, Chiu LM, Guarneros A, et al. Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3H]glutamate in hippocampal nerve endings. Neuropharmacology. 2007 Feb;52(2):598-605. PMID: 17070874.

Nishimura M, Nakanishi T, Yasui A, et al. Serum calcium increases the incidence of arrhythmias during acetate hemodialysis. Am J Kidney Dis. 1992 Feb;19(2):149-55. PMID: 1739097.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C4656

    Clopidol

    Coccidiostat.

    ≥98%
  • A7210

    L-(+)-Ascorbic Acid

    Form of vitamin C found in various plant and fo...

    ≥98%
  • O4531

    Oligomycin A

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • S6134

    Spinorphin, bovine

    Endogenous heptapeptide; P2X3 and N-formylpepti...

    ≥95%
  • P7718

    Pterostilbene

    Stilbene, resveratrol analog.

    ≥98%
  • I0010

    5-(9-Isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine

    Intermediate in the synthesis of purine analogs...

    ≥98%
  • R176485

    Remdesivir

    SARS-CoV-2 inhibitor

    ≥99%
  • N5766

    L-(-)-Norepinephrine Bitartrate Monohydrate

    Endogenous hormone and neurotransmitter involve...

    ≥98%
  • K0133

    Kainic Acid

    Excitatory amino acid found in seaweed; AMPA an...

    ≥98%
  • L186858

    Levomefolic acid

    Folic acid derivative

    ≥98%
  • T0104

    Taxol Side Chain Methyl Ester

    Side chain attached to various taxanes.

    ≥96%
  • T0002

    T2 Toxin

    Trichothecene mycotoxin produced by Fusarium, a...

    ≥98%
  • P3563

    Piperlonguminine

    Found in Piper longum.

    ≥99%
  • S8009

    Substance P (7-11)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • A5170

    Amrinone

    Pyridine; PDE3 inhibitor.

    ≥98%
  • T0142

    TAK-733

    MEK inhibitor.

    ≥98%
  • R1777

    9-cis-Retinoic Acid

    Vitamin A derivative; RAR and RXR agonist.

    ≥99%
  • D0182

    Daunorubicin Hydrochloride

    Anthracycline, DNA intercalator; topoisomerase ...

    ≥98%
  • P982691

    Pyridostatin Trifluoroacetate Salt

    G-quadruplex ligand; DNA breakage inducer.

    ≥95%
  • N5072

    NMS-1286937

    PLK1 inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only