Description
Penciclovir is a guanosine nucleoside analog that prevents viral replication by inducing lethal mutations and inhibits DNA polymerase. Penciclovir exhibits antiviral activity and is clinically used to treat herpes virus infections.
| Product Unit Size | Cost | Quantity | Stock |
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Penciclovir is a guanosine nucleoside analog that prevents viral replication by inducing lethal mutations and inhibits DNA polymerase. Penciclovir exhibits antiviral activity and is clinically used to treat herpes virus infections.
| Cas No. | 39809-25-1 |
|---|---|
| Purity | ≥98% |
| Formula | C10H15N5O3 |
| Formula Wt. | 253.26 |
| Chemical Name | 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxy- methylbutyl]-6H-purin-6-one |
| IUPAC Name | 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one |
| Synonym | Denavir, Vectavir |
| Melting Point | 275-277°C |
| Solubility | Soluble in water, DMSO. |
| Appearance | White to off-white crystal powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Deval J. Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. PMID: 19228073.
Villarreal EC. Current and potential therapies for the treatment of herpes-virus infections. Prog Drug Res. 2003;60:263-307. PMID: 12790345.
Balzarini J, Bohman C, Walker RT, et al. Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol Pharmacol. 1994 Jun;45(6):1253-8. PMID: 8022417.
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