• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Phentolamine Hydrochloride

Phentolamine Hydrochloride

Product ID P2817
Cas No. 73-05-2
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $86.80 In stock
100 mg $129.80 In stock
500 mg $501.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Phentolamine is a nonselective α-adrenergic receptor antagonist that exhibits vasodilatory and antihypertensive activities. Phentolamine is occasionally used to treat erectile dysfunction. In vivo, phentolamine inhibits fructose-induced increases in blood pressure and activates ATP-sensitive K+ channels, altering Ca2+ signaling.

Product Info

Cas No.

73-05-2

Purity

≥98%

Formula

C17H19N3O • HCl

Formula Wt.

317.81

Chemical Name

3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methyl- phenyl)amino]phenol hydrochloride

IUPAC Name

3-[N-(4, 5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;hydrochloride

Melting Point

239-240°C

Solubility

Soluble in water (1g/50mL) and alcohol (1g/70mL). Slightly soluble in chloroform. Practically insoluble in acetone and ethyl acetate.

Appearance

Brown Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P2817 MSDS PDF

Info Sheet

P2817 Info Sheet PDF

References

Zhou K, Kumar U, Yuen VG, et al. The effects of phentolamine on fructose-fed rats. Can J Physiol Pharmacol. 2012 Aug;90(8):1075-85. PMID: 22783820.

Ahn SW, Kim SH, Kim JH, et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res. 2010 Mar;33(3):479-89. PMID: 20361315.

Dinsmore WW, Wyllie MG. Vasoactive intestinal polypeptide/phentolamine for intracavernosal injection in erectile dysfunction. BJU Int. 2008 Sep;102(8):933-7. PMID: 18485029.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D0004

    Dabrafenib

    B-Raf and c-Raf inhibitor.

    ≥98%
  • B011458

    Baloxavir

    Cap-dependent endonuclease inhibitor

    ≥ 99%
  • T3454

    Tinidazole

    Nitroimidazole, binds DNA; nucleic acid synthes...

    ≥98%
  • C691325

    Cridanimod

    STING agonist

    ≥99%
  • I7457

    1-Isothiocyanato-6-(methylsulfinyl)-hexane

    Synthetic derivative of 6-methylsulfinyl-hexane...

    ≥98%
  • E7230

    Ethambutol Dihydrochloride

    Arabinosyl transferase inhibitor.

    ≥98%
  • I0516

    I-BET151

    BRD2/3/4 inhibitor.

    ≥98%
  • R1780

    trans-Retinoic Acid

    Vitamin A carboxylic acid; RAR agonist.

    ≥98%
  • B6806

    Bradykinin (2-9)

    Natriuretic, vasodilatory peptide fragment; B1/...

    ≥95%
  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%
  • C4659

    Clobetasol Propionate

    Corticosteroid; glucocorticoid agonist.

    ≥98%
  • A1330

    Adipokinetic Hormone

    Neuropeptide hormone found in insects, involved...

    ≥95%
  • M4004

    MK-2461

    MET, FGFR, PDGFR inhibitor.

    ≥99%
  • A744789

    ASTX660

    Antitumor

    ≥98%
  • M0172

    Mastoparan

    Antimicrobial peptide found in Vespula lewisii,...

    ≥95%
  • A7669

    A-type Natriuretic Peptide (1-28), rat

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥95%
  • T0104

    Taxol Side Chain Methyl Ester

    Side chain attached to various taxanes.

    ≥96%
  • S7868

    SRT1720 Hydrochloride

    SIRT 1 activator, SIRT3 inhibitor.

    ≥98%
  • C1609

    Cecropin B

    Antimicrobial peptide found in Hyalophora cecro...

    ≥95%
  • R8076

    Rutin Hydrate

    Flavonoid glycoside found in fruit, asparagus, ...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only