• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Phenylbutyrate Sodium

Phenylbutyrate Sodium

Product ID P2815
Cas No. 1716-12-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $86.80 In stock
5 g $282.20 In stock
25 g $1,125.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Phenylbutyrate is an inhibitor of histone deacetylase (HDAC) that exhibits neuroprotective and anticancer chemotherapeutic activities. In cellular and animal models of pancreatic cancer, phenylbutyrate inhibits cellular proliferation and tumor growth. This compound is clinically used to treat urea cycle disorders, as it allows excretion of excess nitrogen waste. In animal models of Alzheimer’s disease, phenylbutyrate prevents neuronal loss and normalizes brain pathology.

Product Info

Cas No.

1716-12-7

Purity

≥98%

Formula

C10H11O2Na

Formula Wt.

186.18

Chemical Name

Benzenebutanoic acid, sodium salt

IUPAC Name

sodium;4-phenylbutanoate

Synonym

Buphenyl, Sodium 4-phenylbutyrate, Tributyrate

Melting Point

214-220°C

Solubility

Soluble in water, ethanol, DMSO.

Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P2815 MSDS PDF

Info Sheet

P2815 Info Sheet PDF

Brochures

Epigenetic Modifiers Booklet

References

Jiang Z, He Q, Wezeman J, et al. A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple pathways. Geroscience. 2024 Oct;46(5):4855-4868. PMID: 38755466.

Cuadrado-Tejedor M, Ricobaraza AL, Torrijo R, et al. Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model. Curr Pharm Des. 2013;19(28):5076-84. PMID: 23448463.

Dovzhanskiy DI, Hartwig W, Lázár NG, et al. Growth inhibition of pancreatic cancer by experimental treatment with 4-phenylbutyrate is associated with increased expression of Connexin 43. Oncol Res. 2012;20(2-3):103-11. PMID: 23193916.

Iannitti T, Palmieri B. Clinical and experimental applications of sodium phenylbutyrate. Drugs R D. 2011 Sep 1;11(3):227-49. PMID: 21902286.

Batshaw ML, MacArthur RB, Tuchman M. Alternative pathway therapy for urea cycle disorders: twenty years later. J Pediatr. 2001 Jan;138(1 Suppl):S46-54; Erratum in: J Pediatr 2002 Apr;140(4):490. PMID: 11148549.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H000051

    H-151

    STING antagonist

    ≥99%
  • N3310

    Nicotinamide

    Amide form of vitamin B3 required for productio...

    ≥98%
  • M403007

    MK-3697

    Orexin 2 receptor antagonist

    ≥98%
  • A6971

    ARRY-162

    MEK1/2 and ERK inhibitor.

    ≥99%
  • S7871

    Stresscopin, human

    Peptide, urocortin III analog; CRFR2 agonist.

    ≥95%
  • R3475

    Risperidone

    Benzisoxazole; 5-HT7 and NMDA agonist, D-amino ...

    ≥98%
  • Z8401

    Z-VAD-FMK

    Non-specific caspase inhibitor used to prevent ...

    ≥95%
  • E6994

    Erythromycin

    Macrolide; protein translation inhibitor, mamma...

    ≥94%
  • S771337

    STING Agonist-1

    Indirect activator of STING signaling

    ≥98%
  • C451338

    Clioquinol

    Antifungal agent with neuroprotective activity....

    ≥98%
  • A5170

    Amrinone

    Pyridine; PDE3 inhibitor.

    ≥98%
  • O9596

    Oxybutynin Hydrochloride

    mAChR antagonist.

    ≥98%
  • A0248

    BAM-12P

    Peptide, cleavage product of proenkephalin; κO...

    ≥95%
  • T5870

    Torin 1

    Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...

    ≥98%
  • I7457

    1-Isothiocyanato-6-(methylsulfinyl)-hexane

    Synthetic derivative of 6-methylsulfinyl-hexane...

    ≥98%
  • A4849

    Amyloid-β (25-35)

    Endogenous APP peptide cleavage product, primar...

    ≥95%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • A4521

    Alfacalcidol

    Vitamin D analog.

    ≥98%
  • A985128

    AZD-7648

    DNA-PK inhibitor.

    ≥98%
  • U6856

    Urocortin II, human

    Endogenous peptide, involved in stress signalin...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only