Description
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Cas No. | 26145-48-2 |
|---|---|
| Purity | ≥95% |
| Formula | C52H82N16O13S |
| Formula Wt. | 1171.41 |
| IUPAC Name | N-[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[1-[4-amino-4-oxo-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]pyrrolidine-2-carbonyl]amino]butanediamide |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.
Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.
Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.
Peptide, binds heparin.
Mast cell stabilizer; TRPV2 antagonist, PDGFR i...
Selective 5-HT6 receptor antagonist
Endogenous neuropeptide hormone, lowers extrace...
Pyridine; PDE3 inhibitor.
Mas antagonist.
α3β2, α3β4, α4β2 nAChR antagonist, indire...
Semi-synthetic vinca alkaloid found in Catharan...
Immunostimulator, adjuvant.
Bosutinib isomer; Src and Abl inhibitor.
Terpene found in various plant and fruit source...
α1A-adrenergic antagonist.
Calcitonin-family peptide, involved in vasodila...
Peptide fragment of VSV; LDLR agonist.
α-glucosidase inhibitor.
AT1 inhibitor.
CRTH2 inhibitor.
Pyrimidine analog; inhibits thymidylate synthas...
Peptide, derivative of AT I, cleavage product o...
BK/SK, Kv1, Kv3, TASK-2 K+ channel blocker, vol...