Description
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Cas No. | 26145-48-2 |
|---|---|
| Purity | ≥95% |
| Formula | C52H82N16O13S |
| Formula Wt. | 1171.41 |
| IUPAC Name | N-[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[1-[4-amino-4-oxo-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]pyrrolidine-2-carbonyl]amino]butanediamide |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.
Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.
Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.
Proteasome antigen.
BTK inhibitor.
H+/K+ ATPase inhibitor.
Endogenous opioid peptide; μOr agonist.
Peptide fragment of VSV; LDLR agonist.
Mycotoxin produced by Fusarium fungi that infec...
Potential VEGFR2, Met, RET, Axl, Ron, PDGFR, FG...
EGFR inhibitor.
Sirtuin inhibitor and iron chelator.
Derivative of methyl caffeate, hydroxycinnamic ...
Somewhat selective in inhibiting COX-2 over COX...
DNA alkylator.
Endogenous cardiomodulatory peptide; NPR-A agon...
Vitamin A carboxylic acid; RAR agonist.
Isoquinoline alkaloid found in a variety of pla...
Benzyl taxol analog; potential microtubule depo...
PI3K inhibitor.
Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...
DP1 antagonist.
Chalcone; SIRT activator, GABA-A positive modul...