Description
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Phyllomedusin is an amphibian tachykinin neuropeptide that activates neurokinin 1 (NK1) receptors. Phyllomedusin induces contractions in ileal longitudinal muscle and stimulates spasmogenic activity in stomach smooth muscle.
| Cas No. | 26145-48-2 |
|---|---|
| Purity | ≥95% |
| Formula | C52H82N16O13S |
| Formula Wt. | 1171.41 |
| IUPAC Name | N-[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[1-[4-amino-4-oxo-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]pyrrolidine-2-carbonyl]amino]butanediamide |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ganjiwale AD, Cowsik SM. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. PMID: 19409496.
Bertaccini G, Coruzzi G. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. PMID: 882154.
Széli J, Molina E, Zappia L, et al. Action of some natural polypeptides on the longitudinal muscle of the guinea pig ileum. Eur J Pharmacol. 1977 Jun 1;43(3):285-7. PMID: 872882.
Resveratrol prodrug; potential SIRT1 activator....
VEGFR1/2/3, PDGFR, c-Kit, RET inhibitor.
Peptide, contains two cell-penetrating sequence...
MAO-A/B inhibitor.
SERT, NET, MAO inhibitor.
Benzimidazole; microtubule polymerization inhib...
JAK1/2/3 inhibitor.
PRMT5/MTA complex inhibitor
Somewhat selective in inhibiting COX-2 over COX...
Imidazole; 14-α demethylase inhibitor, potenti...
Triterpenoid
Glucosinolate found in cruciferous vegetables.<...
Imidzoline derivative; MDM2 inhibitor.
Immunodominant peptide epitope occurring in mul...
Endogenous amino acid, also found in meat, dair...
G-quadruplex ligand; DNA breakage inducer.
FIASMA; α1- and β1/2-adrenergic antagonist.
Synthetic catechol; ER agonist, microtubule pol...
Diterpene found in Taxus; potential microtubule...
14-α demethylase inhibitor.