Physcion

Name: Physcion
SKU: P2995
Availability: InStock

Product ID P2995

Cas No. 521-61-9

Purity ≥96%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Physcion is an anthraquinone originally found in several plant sources, including Microsporum, Psorospermum, Rhamnus, and Rheum. Physcion exhibits anticancer, antibiotic, and anti-inflammatory activities. In cervical carcinoma cells, physcion induces apoptosis by downregulating expression of Bcl-2 and upregulating expression of Bax and activation of caspase 3. Physcion also exhibits antibacterial activity against Staphylococcus, Pseudomonas, and Escherichia, as well as antifungal activity against Candida and Aspergillus. In animal models, physcion inhibits iNOS expression and decreases edema volume.

Product Info

Cas No.	521-61-9
Purity	≥96%
Formula	C₁₆H₁₂O₅
Formula Wt.	284.26
Chemical Name	1,8-Dihydroxy-3-methoxy-6-methylanthraquinone
IUPAC Name	1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione
Synonym	Parietin, Physcione, Rheochrysidin.
Melting Point	203-207C
Solubility	Insoluble in water, slightly soluble in cold alcohol, soluble in boiling alcohol, soluble in benzene, chloroform, ether, acetone, acetic acid, sodium hydroxide and hot sodium carbonate solution, and very slightly soluble in petroleum ether.
Appearance	Yellow powder

Shipping and Storage

Store Temp	4°C
Ship Temp	ambient

Downloads

MSDS	P2995 MSDS PDF
Info Sheet	P2995 Info Sheet PDF

References

Wijesekara I, Zhang C, Van Ta Q, et al. Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells. Microbiol Res. 2014 Apr;169(4):255-61. PMID: 24071573.

Locatelli M, Epifano F, Genovese S, et al. Anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of Rhamnus catharticus and R. orbiculatus. Nat Prod Commun. 2011 Sep;6(9):1275-80. PMID: 21941897.

Ghosh S, Das Sarma M, Patra A, et al. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn. J Pharm Pharmacol. 2010 Sep;62(9):1158-66. PMID: 20796195.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Physcion

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Anagrelide

Dihydrochelerythrine

Pipemidic Acid

Triacetyl Aloe-emodin (Impurity A)

Nifursol

N-(4-Carbethoxyphenyl)retinamide

20S-Ginsenoside Rg3

Mastoparan X

7-Aminoactinomycin D

Dapiprazole Hydrochloride

Asparaginase

Manidipine Dihydrochloride

MSA-2

Tobramycin, Free Base

Solanesol

(−)-Epicatechin Gallate

Kahweol Oleate

Allatostatin I

K252b

Recombinant Tp-chimeric protein

Footer