• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Polydatin

Polydatin

Product ID P5845
Cas No. 65914-17-2
Purity ≥97%
Product Unit SizeCostQuantityStock
250 mg $67.80 In stock
1 g $127.90 In stock
5 g $255.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Polydatin is a resveratrol-related glucoside originally found in Polygonum cuspidatum. Polydatin exhibits anticancer, anti-inflammatory, antioxidative, and anti-allergic activities. In lung cancer cells, polydatin downregulates expression of cyclin D1 and Bcl-2 and upregulates expression of Bax, inducing cell cycle arrest and apoptosis. In animal models of sepsis, polydatin decreases sepsis-induced mortality and lung injury by suppressing production of COX-2, iNOS, and inflammatory cytokines. Polydatin also decreases the loss of mucosal barrier integrity in the small intestine due to OVA-induced allergy by inhibiting mast cell degranulation.

Product Info

Cas No.

65914-17-2

Purity

≥97%

Formula

C20H22O8

Formula Wt.

390.38

Chemical Name

3-Hydroxy-5-(2-(4-hydroxyphenyl)ethenyl)phenyl-beta-D-glucoside

IUPAC Name

(2S,3R,4S,5S, 6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]phenoxy]-6- (hydroxymethyl)oxane-3,4,5-triol

Synonym

Resveratrol 3-β-mono-D-glucoside

Melting Point

223-226°C

Solubility

Soluble in methanol, ethanol acetone, hot water or ethyl acetate.

Appearance

White powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P5845 MSDS PDF

Info Sheet

P5845 Info Sheet PDF

References

Zhang Y, Zhuang Z, Meng Q, et al. Polydatin inhibits growth of lung cancer cells by inducing apoptosis and causing cell cycle arrest. Oncol Lett. 2014 Jan;7(1):295-301. PMID: 24348867.

Yang B, Li JJ, Cao JJ, et al. Polydatin attenuated food allergy via store-operated calcium channels in mast cell. World J Gastroenterol. 2013 Jul 7;19(25):3980-9. PMID: 23840142.

Li XH, Gong X, Zhang L, et al. Protective effects of polydatin on septic lung injury in mice via upregulation of HO-1. Mediators Inflamm. 2013;2013:354087. PMID: 23431240.

Wu MJ, Gong X, Jiang R, et al. Polydatin protects against lipopolysaccharide-induced fulminant hepatic failure in D-galactosamine-sensitized mice. Int J Immunopathol Pharmacol. 2012 Oct-Dec;25(4):923-34. PMID: 23298483.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H9612

    Hydrocortisone 21-Acetate

    Steroid hormone involved in stress signaling; g...

    ≥98%
  • C0171

    Carboplatin

    Pt-based DNA cross-linker.

    ≥99%
  • C1621

    CEF4

    Peptide, vSrc-induced cytokine.

    ≥95%
  • M400220

    MK-2206 Dihydrochloride

    Akt inhibitor.

    ≥99%
  • A2400

    AG-1024

    Tyrphostin; IGF-1R inhibitor.

    ≥98%
  • E6257

    Epothilone B

    Microtubule depolymerization inhibitor.

    ≥98%
  • S8146

    Sulindac Sulfone

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • V0147

    Valproic Acid Sodium

    T-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • I2056

    Ifosfamide

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • E0929

    Echinacoside

    Phenylethanoid glycoside found in Echinacea.

    ≥98%
  • R2516

    RGES

    Peptide, used as control to measure RGDS peptid...

    ≥95%
  • I5830

    Iohexol

    Low osmolarity contrast agent used for imaging ...

    ≥98%
  • F334451

    Filipin Complex

    A probe for cholesterol in biological membranes...

    ≥97%
  • D0262

    Dapiprazole Hydrochloride

    α1-Adrenergic antagonist.

    ≥98%
  • S8098

    SU-1498

    Tyrphostin; VEGFR inhibitor.

    ≥99%
  • C9615

    Cyclosporin B

    Cyclic peptide; calcineurin inhibitor.

    ≥95%
  • V014463

    Valsartan Methyl Ester

    Valsartan impurity

    ≥98%
  • O610291

    Ophiobolin A

    Tetracyclic sesterpenoid phytotoxin.

    ≥98%
  • P4780

    Plumbagin

    Naphthoquinone found in Plumbago.

    ≥98%
  • L1982

    Leupeptin Hemisulfate

    Protease inhibitor.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only