Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
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PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Benzylisoquinoline alkaloid originally found in...
Pentacyclic triterpene found in various plant s...
Glycolic acid ester prodrug of indomethacin, NS...
Smoothened agonist.
Calcium channel blocker.
L-type and T-type Ca2+ and TRP antagonist.
Benzophenanthridine alkaloid found in Garcinia....
ITC, erucin analog.
Alkaloid found in species of Loranthus, Calia, ...
β-lactam; penicillin binding protein inhibitor...
Fatty acid synthase inhibitor.
Triterpenoid
NSAID; COX-2 inhibitor.
Isoflavonoid found in Glycyrrhiza; GABA-A posit...
Mycotoxin contaminant found in cereal grains.
Anthraquinone found in various plant sources; C...
NPC1L1 inhibitor.
ITC, used as chiral agent.
Terpene lactone found in Ginkgo.
Multikinase inhibitor.