Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Peptide; GABA potentiator, NMDA negative allost...
JAK2 inhibitor.
Potential ATP-sensitive K+ channel blocker, pot...
Cembranoid found in Sarcophyton.
PPARγ agonist, AT1 inhibitor.
Nucleoside (thymidine) analog; DNA chain termin...
Benzimidazole; microtubule polymerization inhib...
Endogenous peptide neurotransmitter, involved i...
Used for in vitro fertilization; FIASMA, SERM.<...
Endogenous tripeptide, involved in HPA signalin...
Immunostimulator, adjuvant.
H+/K+ ATPase inhibitor.
Taxane synthesis intermediate.
SERT inhibitor, potential voltage-gated K+ chan...
Caspase 3 substrate.
Semi-synthetic taxane.
Inert clozapine analog, activates specialized G...
Endogenous peptide hormone; motilin agonist.
Found in Cladosporium; PKC inhibitor.
MDM2 inhibitor.