Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Adenosine A2A agonist.
Tryptamine; 5-HT1B/1D agonist, TRPV1 antagonist...
Found in Astragalus membranaceus.
Steroid 5-α-reductase inhibitor.
Triterpene saponin found in species of Panax; Î...
CDK4/6 inhibitor.
Cysteine-ITC conjugate, antioxidant.
Impurity of everolimus
Bisaniline pyrimidine; pan-kinase inhibitor.
Hexokinase inhibitor, aerobic glycolysis inhibi...
Vitamin D prodrug produced by fungi and alfalfa...
Cationic lipid polypeptide, mixture of polymyxi...
Proteasome inhibitor.
Glutathione-S-transferase inhibitor.
Dynamin inhibitor.
β2-adrenergic agonist.
Benzimidazole; microtubule polymerization inhib...
Peptide, HIV-1 RT A2.1 epitope.
Aminoglycoside; protein translation inhibitor.<...
Diterpenoid found in Rabdosia rubescens; potent...