Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Protein translation inhibitor, peptidyl transfe...
Alkaloid found in species of Loranthus, Calia, ...
Triterpene saponin found in Bupleurum.
Chloramphenicol derivative; protein translation...
Amphibian tachykinin neuropeptide.
Apoptosis inducing agent.
Cysteine-ITC conjugate, antioxidant; aldehyde d...
Monoterpene; nAChR antagonist.
Nav1.8 Na+ channel blocker, potential Nav1.5 Na...
Derivative of camptothecin.
Minor kavalactone originally found in Piper met...
Dihydropyridine; L-type and N-type Ca2+ channel...
B cell epitope found on hepatitis B viral core ...
Protein translocation inhibitor.
Synthetic taxol synthesis intermediate; microtu...
PI3K and HDAC inhibitor.
Oligodendrocyte antigen used to induce EAE.
Analog of glutamate
Isoflavone daidzein derivative found in Puerari...
Imidazole; HMG-CoA reductase, 14-α demethylase...