Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Centrally acting muscle relaxant.
Hexokinase inhibitor, aerobic glycolysis inhibi...
Endogenous peptide, produced by activation of P...
Endogenous amino sugar precursor required for p...
Electron carrier used to study dehydrogenase el...
Pentacyclic triterpene found in various plant s...
Recombinant protein containing Treponema pallid...
mTOR inhibitor.
EGFR inhibitor.
Flavanone found in species of Citrus. Naringen...
ATP competitive CDK inhibitor.
Terpene found in various plant and fruit source...
Nucleoside (thymidine) analog; DNA chain termin...
Imidazole; 14-α demethylase, H+/K+ ATPase, Na+...
Impurity of diclofenac
Islet α/β cell proliferation stimulator.
Taxane synthesis intermediate.
Non-nitrogen bisphosphonate; mitochondrial ATP/...
SGLT2 inhibitor
Alkaloid produced by Streptomyces, precursor in...