Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Endogenous peptide hormone, involved in intesti...
Semi-synthetic vinca alkaloid from Catharanthus...
Mineralocorticoid, aldosterone, AR antagonist, ...
Triterpene aglycone found in Radix Astragali; t...
Synthetic derivative of 6-methylsulfinyl-hexane...
mTOR inhibitor.
Avermectin; glu-gated Cl- channel activator, Gl...
Semi-synthetic analog of taxol; microtubule dep...
Fluoroquinolone; topoisomerase IV and bacterial...
Rapamycin impurity
σ1 antagonist.
CB1 inverse agonist.
Polyene macrolide, induces pore formation in fu...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Purine (hypoxanthine) analog; xanthine oxidase ...
Glycopeptide, binds D-Ala-D-Ala; cell wall synt...
Nucleobase (adenine) analog; DNA polymerase inh...
Thiopurine antimetabolite; PRPP amidotransferas...
p110α and p110γ PI3K inhibitor.
MEK 1/2 inhibitor.