Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
5-HT2A and TRPV1 antagonist, potential α1-adre...
FIASMA, histamine H1 inverse agonist, 5-HT2A, D...
PI3K inhibitor.
ACE inhibitor.
Isoflavone daidzein derivative found in Puerari...
Immunodominant peptide epitope occurring in mul...
Mycotoxin produced by Fusarium fungi that infec...
Juvenille insect growth hormone analog.
Jumonji histone demethylase inhibitor.
Polypeptide; serine protease inhibitor.
Macrolide; F1F0 ATP synthase inhibitor.
Alkaloid found in Galanthus, Narcissus, Leucoju...
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
Fluoroquinolone; topoisomerase IV and bacterial...
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
Prolyl hydroxylase inhibitor.
MEK1 inhibitor.
Allosteric inhibitor
Neurotoxin found in puffer fish; site 1 voltage...
TGF-β1 inhibitor.