Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Mycotoxin produced by Aspergillus; actin polyme...
p110δ PI3K inhibitor.
Aminoglycoside; protein translation inhibitor.<...
Cyclic peptide; calcineurin inhibitor.
γ-Secretase inhibitor.
Mycotoxin produced by Fusarium; ER agonist.
Synthesis impurity
Calcineurin inhibitor, potential TRPV1 agonist....
EGFR inhibitor.
Antimicrobial peptide found in bee and wasp ven...
Endogenous peptide hormone, involved in cell gr...
Proteasome inhibitor.
SIRT1/2 inhibitor, indirect p53 activator.
p110γ PI3K inhibitor.
Endogenous neuropeptide hormone, lowers extrace...
Coumarin, more potent isomer; VKORC1 inhibitor....
Pyrimidine nucleoside (cytidine) analog; DNA ch...
Non-depolarizing NMJ blocker; AChR antagonist.<...
Mycotoxin that has structural similarity to est...
AR antagonist.