Description
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
PP-121 an inhibitor of p110α PI3K, DNA-PK, mTORC1/2, Abl, Hck, Src, VEGFR2, and PDGFR that exhibits anticancer activity by inhibiting cellular proliferation.
| Cas No. | 1092788-83-4 |
|---|---|
| Purity | ≥98% |
| Formula | C17H17N7 |
| Formula Wt. | 319.36 |
| IUPAC Name | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | DMSO 64 mg/mL (200.4 mM) Ethanol 2 mg/mL (6.26 mM) Water Insoluble |
| Appearance | White Crystal Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Apsel B, Blair JA, Gonzalez B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. PMID: 18849971.
Imaging agent; Maillard reaction inhibitor.
Endogenous sugar produced from glucose, require...
Natriuretic, vasodilatory peptide fragment; B1/...
Endogenous peptide hormone fragment, involved i...
Ester found in Spiraea, Betula, and Gaultheria;...
Cyclic depsipeptide is a secondary metabolite i...
Lignin found in Sesamin indicum;
Orexin 2 receptor antagonist
Lactone found in fungi such as Eupenicillium; g...
Primarily targets HDAC1
Promotes degradation of cIAP1
Endogenous neuropeptide hormone, lowers extrace...
Synthetic analog of 1,4-naphthoquinone, precurs...
Endogenous peptide hormone, involved in intesti...
Rapamycin analog
Tropane alkaloid found in Solanaceae plants; α...
Corticosteroid
Endogenous peptide hormone, counteracts insulin...
JAK3 inhibitor.
Alkaloid compound originally found in Corydalis...