LKT Labs

Biochemicals for Life Science Research

Prednisone Acetate

Prednisone Acetate

Product ID P7021
Cas No. 125-10-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $62.90 In stock
5 g $208.70 In stock
25 g $729.40 In stock
Bulk Quote

Quicklinks

Description

Prednisone is a synthetic corticosteroid/glucocorticoid that exhibits no biological activity until converted to its active metabolite, prednisolone. Once converted, this compound exhibits anti-inflammatory, immunosuppressive, anti-allergic, neuroprotective, and anticancer chemotherapeutic activities. Prednisone is one component of the CHOP chemotherapeutic cocktail that is clinically used to treat leukemias and lymphomas; in animal models of subarachnoid hemorrhage, CHOP inhibits neuronal apoptosis. Prednisone also inhibits expression of IL-6 and is clinically used to treat rheumatoid arthritis.

Product Info

Cas No.

125-10-0
Purity

≥98%
Formula

C23H28O6
Formula Wt.

400.46
Chemical Name

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione acetate
IUPAC Name

[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8, 9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Synonym

Prednisone 21-acetate, Pred Forte
Melting Point

226-232°C (dec)
Solubility

Insoluble in water. Slightly soluble in ethanol.
Appearance

White or almost white Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

P7021 MSDS PDF
Info Sheet

P7021 Info Sheet PDF

References

Hoy SM. Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma. Drugs. 2012 Oct 1;72(14):1929-50. PMID: 22950536.

Clarke L, Kirwan J. Efficacy, safety and mechanism of action of modified-release prednisone in rheumatoid arthritis. Ther Adv Musculoskelet Dis. 2012 Jun;4(3):159-66. PMID: 22850902.

He Z, Ostrowski RP, Sun X, et al. CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage. Stroke. 2012 Feb;43(2):484-90. PMID: 22180248.

Manns MP, Strassburg CP. Therapeutic strategies for autoimmune hepatitis. Dig Dis. 2011;29(4):411-5. PMID: 21894012.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L8276

    Luteinizing Hormone Releasing Hormone

    Endogenous peptide hormone; GnRH agonist.

    ≥98%
  • P3463

    Piperacillin Sodium

    β-lactam; penicillin binding protein inhibitor...

    ≥95%
  • P0256

    Pantoprazole Sodium Sesquihydrate

    H+/K+ ATPase and ROCK-2 inhibitor.

    ≥98%
  • E5057

    Emodin

    Anthraquinone found in various plant sources; C...

    ≥95%
  • L0284

    Lavendustin A

    Tyrosine kinase inhibitor.

    ≥97%
  • I5313

    Indinavir Sulfate

    HIV protease, GLUT4, calpain inhibitor.

    ≥99%
  • P2918

    Phenylethyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • K0054

    Kanamycin B

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • M568270

    Mogroside V

    Triterpenoid

    ≥98%
  • E6257

    Epothilone B

    Microtubule depolymerization inhibitor.

    ≥98%
  • T2835

    6-Thioguanine

    Nucleotide (guanine) analog, prevents guanine s...

    ≥90%
  • B6856

    5-Bromo-2′-Deoxyuridine

    Nucleoside (thymidine) analog.

    ≥98%
  • A5314

    Dehydroandrographolide

    Labdane diterpene found in Andrographis.

    ≥98%
  • I5208

    INCB-28060

    c-MET inhibitor.

    ≥98%
  • D582703

    Dorsomorphin

    Inhibitor of ALK2, ALK3, ALK6, and AMPK.

    ≥98%
  • F4680

    Flutamide

    Non-steroid; AR antagonist.

    ≥98%
  • T564098

    Tocored

    Tocopherol analog
  • G1855

    Gentiopicroside

    Secoiridoid glycoside found in Gentiana and Cep...

    ≥95%
  • G1408

    GDC-0449

    Smo inhibitor.

    ≥98%
  • M1877

    Methylprednisolone

    Synthetic steroid; glucocorticoid agonist.

    ≥96%