LKT Labs

Biochemicals for Life Science Research

Progesterone

Progesterone

Product ID P6854
Cas No. 57-83-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $43.40 In stock
25 g $126.30 In stock
100 g $457.90 In stock
Bulk Quote

Quicklinks

Description

Progesterone is an endogenous steroid hormone that activates progesterone receptors (PRs) and inhibits mineralocorticoid receptors (MRs), nicotinic acetylcholine receptors (nAChRs), and σ1/2 receptors. Progesterone exhibits neuroprotective activity, inducing myelin sheath formation and supporting neurotransmission. Progesterone also plays a significant role in reproduction and mammary gland development. Clinically, this compound is used to prevent preterm birth and is occasionally used in hormone replacement therapy (HRT).

Product Info

Cas No.

57-83-0
Purity

≥98%
Formula

C21H30O2
Formula Wt.

314.47
Chemical Name

Pregn-4-ene-3,20-dione
IUPAC Name

(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14, 15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Synonym

Corlutin, Gesterol, Luteol, Prolutone, Prolidon, Syngesterone, Utrogestan
Melting Point

128-132°C
Solubility

Insoluble in water. Soluble in alcohol, acetone or dioxane.
Appearance

White or almost white crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

P6854 MSDS PDF
Info Sheet

P6854 Info Sheet PDF

References

Johannessen M, Fontanilla D, Mavlyutov T, et al. Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels. Am J Physiol Cell Physiol. 2011 Feb;300(2):C328-37. Erratum in: Am J Physiol Cell Physiol. 2013 Nov 1;305(9):C997. PMID: 21084640.

da Fonseca EB, Bittar RE, Carvalho MH, et al. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study. Am J Obstet Gynecol. 2003 Feb;188(2):419-24. PMID: 12592250.

Baulieu E, Schumacher M. Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids. 2000 Oct-Nov;65(10-11):605-12. PMID: 11108866.

Rupprecht R, Reul JM, van Steensel B, et al. Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur J Pharmacol. 1993 Oct 15;247(2):145-54. PMID: 8282004.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M177531

    Menaquinone-9

    2-methyl-1,4-naphthoquinone derivative

    ≥99%
  • H9803

    Hyaluronic Acid Sodium (0.2 -5 kDA)

    Glycosaminoglycan
  • P7718

    Pterostilbene

    Stilbene, resveratrol analog.

    ≥98%
  • S7717

    Sterigmatocystin

    Mycotoxin produced by Aspergillus; carcinogen.<...

    ≥98%
  • A0961

    Adrenocorticotropic Hormone (1-39), rat

    Endogenous peptide hormone, involved in stress ...

    ≥95%
  • R0247

    Raltegravir

    HIV integrase inhibitor.

    ≥99%
  • D5992

    Doxapram Hydrochloride Hydrate

    K+ channel blocker, catecholamine release stimu...

    ≥98%
  • H1657

    Heparin-binding Peptide

    Peptide, binds heparin.

    ≥95%
  • M5793

    Moxifloxacin Free Base

    Fluoroquinolone; topoisomerase IV, topoisomeras...

    ≥98%
  • A5378

    Antimycin A

    Oxidative phosphorylation inhibitor.
  • F5766

    Forchlorfenuron

    Synthetic cytokinin, plant growth regulator; fi...

    ≥98%
  • D1720

    Deferiprone

    Iron chelator.

    ≥99%
  • T9946

    Tylosin Phosphate

    Macrolide; peptidyl transferase inhibitor, prot...

    ≥90%
  • A016495

    5-Aminopyrimidine

    Building block

    ≥98%
  • W5727

    Wogonoside

    Flavonoid glycoside found in Scutellaria.

    ≥98%
  • D5611

    Docosahexaenoic Acid (all cis-4,7,10,13,16,19) Methyl Ester

    Essential fatty acid found in fish oil, involve...

    ≥99%
  • P6802

    Pranoprofen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • H9726

    Hygromycin B

    Protein translocation inhibitor.

    ≥95.0%
  • L960004

    LY-404187

    Selective positive allosteric modulator of AMPA...

    ≥98%
  • G3453

    20(S)-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%